Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | F13A1 | P00488 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 3/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TTR | P02766 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19520263 | 0.84 | ALDH1A1 (0.60) | KDM4EMEN1KMT2AALDH1A1HDAC2 | |
| SCHEMBL106904 | 0.83 | ESR1 (0.50) | KDM4EF13A1ESR1ESR2CYP19A1 | |
| SCHEMBL691976 | 0.81 | TRPV1 (0.49) | KDM4EF13A1ESR1ESR2CYP19A1 | |
| SCHEMBL19520243 | 0.81 | ALDH1A1 (0.59) | KDM4EALDH1A1LMNATP53CYP1A2 | |
| SCHEMBL104964 | 0.79 | ESR1 (0.49) | KDM4EF13A1ESR1ESR2CYP19A1 | |
| Raspberryketone SCHEMBL43308 | 0.77 | ALDH1A1 (0.65) | KDM4EF13A1ESR1ESR2CYP19A1 | |
| SCHEMBL11512222 | 0.76 | KDM4E (0.45) | KDM4EF13A1ESR1ESR2CYP19A1 | |
| SCHEMBL11509273 | 0.75 | TDP1 (0.49) | KDM4EF13A1ESR1ESR2CYP19A1 | |
| SCHEMBL21099895 | 0.74 | ALDH1A1 (0.45) | KDM4EMEN1KMT2AALDH1A1TDP1 | |
| SCHEMBL7262945 | 0.73 | CALM1 (0.47) | KDM4EF13A1ESR1ESR2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3448843-B1 | ARYL BETA DIKETONES AND THEIR USE A ODORANTS | GIVAUDAN SA (CH) | 2021-02-24 | — | — | EP | claimed |
| US-10577298-B2 | Aryl beta diketones and their use as odorants | GIVAUDAN S.A. (CH) | 2020-03-03 | — | — | US | claimed |
| US-20190127305-A1 | ARYL BETA DIKETONES AND THEIR USE AS ODORANTS | GIVAUDAN SA (CH) | 2019-05-02 | — | — | US | claimed |
| WO-2017186846-A1 | ARYL BETA DIKETONES AND THEIR USE A ODORANTS | GIVAUDAN SA (CH) | 2017-11-02 | — | — | WO | claimed |
| EP-3448843-B1 | ARYL BETA DIKETONES AND THEIR USE A ODORANTS | GIVAUDAN SA (CH) | 2021-02-24 | — | — | EP | disclosed |
| US-10577298-B2 | Aryl beta diketones and their use as odorants | GIVAUDAN S.A. (CH) | 2020-03-03 | — | — | US | disclosed |
| US-20190127305-A1 | ARYL BETA DIKETONES AND THEIR USE AS ODORANTS | GIVAUDAN SA (CH) | 2019-05-02 | — | — | US | disclosed |
| WO-2017186846-A1 | ARYL BETA DIKETONES AND THEIR USE A ODORANTS | GIVAUDAN SA (CH) | 2017-11-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10577298-B2 | Aryl beta diketones and their use as odorants | CBR3, CBR1, CHRM3 | KDM4E 767/4885F13A1 740/4885ESR1 900/4885 |
| US-20190127305-A1 | ARYL BETA DIKETONES AND THEIR USE AS ODORANTS | CBR3, CBR1, CHRM3 | KDM4E 767/4885F13A1 740/4885ESR1 900/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.