SCHEMBL19523903

SCHEMBL19523903

C/N=C\N(C)/C(C)=C/CCC(C)C

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.31
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19523953 0.71 ALOX15 (0.33) ALOX15TSHR
SCHEMBL17539244 0.68
SCHEMBL19221641 0.68
SCHEMBL22845168 0.66
SCHEMBL108373 0.65
SCHEMBL19523934 0.64 ALDH1A1 (0.30)
Hydrochloric Acid SCHEMBL7431491 0.64 ALOX15 (0.56) ALOX15TSHR
SCHEMBL21689282 0.63
SCHEMBL10926957 0.63 ALOX15 (0.33) ALOX15TSHR
SCHEMBL10926954 0.63 ALOX15 (0.33) ALOX15TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3013823-B1 IMIDAZOLE COMPOUNDS AS MODULATORS OF FSHR AND USES THEREOF MERCK PATENT GMBH (DE) 2017-11-01 EP disclosed