Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRG2 | P18507 | 18/20 | 0.44 |
| ▸ | GABRB3 | P28472 | 18/20 | 0.44 |
| ▸ | GABRA5 | P31644 | 18/20 | 0.44 |
| ▸ | GABRA1 | P14867 | 6/20 | 0.44 |
| ▸ | GABRA3 | P34903 | 6/20 | 0.44 |
| ▸ | GABRA2 | P47869 | 6/20 | 0.44 |
| ▸ | GABRA6 | Q16445 | 5/20 | 0.44 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.44 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | GABRP | O00591 | 1/20 | 0.43 |
| ▸ | GABRD | O14764 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | GABRE | P78334 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16339502 | 0.90 | GABRG2 (0.42) | GABRG2GABRB3GABRA5GABRA1GABRA3 | |
| SCHEMBL7634522 | 0.77 | GABRG2 (0.62) | GABRG2GABRB3GABRA5GABRA1GABRA3 | |
| SCHEMBL2233633 | 0.76 | GABRG2 (0.59) | GABRG2GABRB3GABRA5GABRA1GABRA3 | |
| SCHEMBL16340012 | 0.74 | GABRG2 (0.44) | GABRG2GABRB3GABRA5GABRA1GABRA3 | |
| SCHEMBL24632609 | 0.71 | GABRG2 (0.49) | GABRG2GABRB3GABRA5GABRA1GABRA3 | |
| SCHEMBL16333953 | 0.71 | MAPT (0.39) | GABRG2GABRB3GABRA5GABRA1GABRA3 | |
| SCHEMBL8125584 | 0.71 | GABRG2 (0.45) | GABRG2GABRB3GABRA5GABRA1GABRA3 | |
| SCHEMBL14321045 | 0.69 | HTR1A (0.55) | GABRG2GABRB3GABRA5GABRA1GABRA3 | |
| SCHEMBL430171 | 0.69 | HTR1A (0.51) | GABRG2GABRB3GABRA5GABRA1GABRA3 | |
| SCHEMBL430527 | 0.68 | HTR1A (0.50) | GABRG2GABRB3GABRA5GABRA1GABRA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3013823-B1 | IMIDAZOLE COMPOUNDS AS MODULATORS OF FSHR AND USES THEREOF | MERCK PATENT GMBH (DE) | 2017-11-01 | — | — | EP | disclosed |