Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 14/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SYK | P43405 | 1/20 | 0.45 |
| ▸ | BTK | Q06187 | 4/20 | 0.45 |
| ▸ | ITK | Q08881 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19527814 | 0.97 | EGFR (0.51) | EGFRNPC1RAB9ASYKBTK | |
| SCHEMBL19527732 | 0.85 | NPC1 (0.49) | EGFRNPC1RAB9ASYKMAPT | |
| SCHEMBL19527678 | 0.81 | NPC1 (0.47) | EGFRNPC1RAB9ASYKMAPT | |
| SCHEMBL19527628 | 0.78 | NPC1 (0.47) | EGFRNPC1RAB9ASYKITK | |
| SCHEMBL19527785 | 0.78 | NPC1 (0.47) | EGFRNPC1RAB9ASYKITK | |
| SCHEMBL18995094 | 0.78 | EGFR (0.45) | EGFRSYKBTKITK | |
| SCHEMBL22909438 | 0.76 | SYK (0.56) | EGFRSYKBTKITK | |
| SCHEMBL29729055 | 0.76 | SYK (0.56) | EGFRSYKBTKITK | |
| SCHEMBL19527651 | 0.75 | NPC1 (0.47) | EGFRNPC1RAB9ASYKITK | |
| SCHEMBL18995121 | 0.74 | NPC1 (0.47) | NPC1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2833889-B1 | PROTEIN KINASE C INHIBITORS AND USES THEREOF | RIGEL PHARMACEUTICALS INC (US) | 2017-11-01 | — | — | EP | disclosed |