Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.34 |
| ▸ | CDK1 | P06493 | 1/20 | 0.34 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.34 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.34 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.30 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.30 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19544721 | 0.83 | KDM4E (0.41) | RAB9AALDH1A1MAPT | |
| SCHEMBL19624694 | 0.73 | MAPT (0.46) | KCNH2SLC6A3TAAR1RAB9AHTR2B | |
| SCHEMBL19533624 | 0.71 | ALPL (0.47) | GSK3BCDK5RAB9AMAPK14MAPT | |
| SCHEMBL19533553 | 0.71 | ERBB2 (0.41) | RAB9AALDH1A1MAPT | |
| SCHEMBL19533664 | 0.70 | FFAR1 (0.39) | RAB9AALDH1A1MAPT | |
| SCHEMBL19544636 | 0.69 | KDM4E (0.39) | RAB9AALDH1A1MAPT | |
| SCHEMBL1429353 | 0.67 | SMN1; SMN2 (0.56) | MAPK1RAB9AALDH1A1MAPT | |
| SCHEMBL12037308 | 0.63 | CCNB2 (0.41) | CCNB2CDK1CCNB1GSK3BCDK5 | |
| SCHEMBL31553375 | 0.62 | NOTUM (0.68) | — | |
| SCHEMBL19544616 | 0.61 | ALPL (0.65) | RAB9AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170313683-A1 | BTK INHIBITOR | HUBEI BIO-PHARMACEUTICAL INDUSTRIAL TECHNOLOGICAL INSTITUTE, INC. (CN) | 2017-11-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170313683-A1 | BTK INHIBITOR | BTK, SYK, LYN | KCNH2 3190/4885SLC6A3 2689/4885TAAR1 3157/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.