Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.38 |
| ▸ | ROCK1 | Q13464 | 5/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.36 |
| ▸ | PDE4A | P27815 | 3/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.35 |
| ▸ | NAMPT | P43490 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | TTK | P33981 | 1/20 | 0.34 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.34 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | ACACB | O00763 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19533576 | 0.87 | HRH3 (0.42) | ROCK1ROCK2NAMPTHRH3CYP3A4 | |
| SCHEMBL19544627 | 0.86 | MAPK10 (0.44) | FFAR1HRH3ALDH1A1MAPTRAB9A | |
| SCHEMBL19533582 | 0.84 | HRH3 (0.35) | ROCK2NAMPTHRH3CYP3A4TTK | |
| SCHEMBL19533553 | 0.79 | ERBB2 (0.41) | ALDH1A1MAPTRAB9AACACBNPC1 | |
| SCHEMBL19533663 | 0.74 | ALPL (0.48) | AURKBALDH1A1MAPTRAB9ANPC1 | |
| SCHEMBL19533569 | 0.74 | DHODH (0.41) | TTKALDH1A1MAPTRAB9AACACB | |
| SCHEMBL19544883 | 0.74 | MAPT (0.44) | HRH3ALDH1A1MAPTRAB9ANPC1 | |
| SCHEMBL19533665 | 0.72 | SMN1; SMN2 (0.53) | FFAR1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL19544628 | 0.66 | MAPT (0.65) | FFAR1ALDH1A1MAPTRAB9ANPC1 | |
| SCHEMBL19544658 | 0.65 | SCN9A (0.54) | ALDH1A1MAPTRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170313683-A1 | BTK INHIBITOR | HUBEI BIO-PHARMACEUTICAL INDUSTRIAL TECHNOLOGICAL INSTITUTE, INC. (CN) | 2017-11-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170313683-A1 | BTK INHIBITOR | BTK, SYK, LYN | FFAR1 3296/4885NPY5R 1889/4885ROCK1 330/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.