Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.39 |
| ▸ | GRK6 | P43250 | 1/20 | 0.37 |
| ▸ | TTK | P33981 | 3/20 | 0.37 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.35 |
| ▸ | NAMPT | P43490 | 1/20 | 0.35 |
| ▸ | ACACB | O00763 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.35 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.35 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.35 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.35 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.34 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19533582 | 0.89 | HRH3 (0.35) | HRH3ALDH1A1MAPTGRK6TTK | |
| SCHEMBL19533664 | 0.87 | FFAR1 (0.39) | HRH3ALDH1A1MAPTTTKROCK2 | |
| SCHEMBL19544883 | 0.85 | MAPT (0.44) | HRH3ALDH1A1MAPTGRK6 | |
| SCHEMBL19533553 | 0.79 | ERBB2 (0.41) | ALDH1A1MAPTACACB | |
| SCHEMBL19544607 | 0.77 | MAPK10 (0.43) | HRH3ALDH1A1MAPTTTKMAPK8 | |
| SCHEMBL19544627 | 0.76 | MAPK10 (0.44) | HRH3ALDH1A1MAPT | |
| SCHEMBL19624845 | 0.75 | MAPT (0.54) | HRH3ALDH1A1MAPT | |
| SCHEMBL25060301 | 0.73 | MAPT (0.44) | HRH3ALDH1A1MAPT | |
| SCHEMBL19533574 | 0.71 | ALPL (0.53) | ALDH1A1MAPTMAPK8 | |
| SCHEMBL30837228 | 0.70 | MAP4K4 (0.56) | ALDH1A1MAPTMAP4K4ACACBPARP10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170313683-A1 | BTK INHIBITOR | HUBEI BIO-PHARMACEUTICAL INDUSTRIAL TECHNOLOGICAL INSTITUTE, INC. (CN) | 2017-11-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170313683-A1 | BTK INHIBITOR | BTK, SYK, LYN | HRH3 3404/4885ALDH1A1 4122/4885MAPT 418/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.