Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC2 | O75106 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL400737 | 0.86 | AOC2 (0.50) | AOC2MAPTRAB9APOLBALDH1A1 | |
| SCHEMBL1912118 | 0.82 | AOC2 (0.47) | AOC2MAPTRAB9APOLBALDH1A1 | |
| SCHEMBL403365 | 0.80 | ACACB (0.49) | — | |
| SCHEMBL19534339 | 0.76 | AOC2 (0.45) | AOC2MAPTRAB9APOLBALDH1A1 | |
| SCHEMBL21046322 | 0.76 | AOC2 (0.45) | AOC2MAPTRAB9APOLBALDH1A1 | |
| SCHEMBL21046323 | 0.76 | AOC2 (0.45) | AOC2MAPTRAB9APOLBALDH1A1 | |
| SCHEMBL2409466 | 0.74 | TDP1 (0.57) | AOC2MAPTRAB9APOLBALDH1A1 | |
| SCHEMBL19534337 | 0.74 | AOC2 (0.55) | AOC2MAPTRAB9APOLBALDH1A1 | |
| SCHEMBL12837594 | 0.73 | AOC2 (0.41) | AOC2 | |
| SCHEMBL19534214 | 0.73 | PPARG (0.38) | PPARGPDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017189586-A1 | BENZOYLGLYCINE DERIVATIVES AND METHODS OF MAKING AND USING SAME | DUKE UNIVERSITY (US) | 2017-11-02 | — | — | WO | disclosed |