Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC2 | O75106 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19534339 | 1.00 | AOC2 (0.45) | AOC2MAPTRAB9AALDH1A1MEN1 | |
| SCHEMBL21046323 | 1.00 | AOC2 (0.45) | AOC2MAPTRAB9AALDH1A1MEN1 | |
| SCHEMBL19520703 | 0.81 | ADAMTS5 (0.47) | RAB9AALDH1A1TDP1LMNA | |
| SCHEMBL19520702 | 0.81 | ADAMTS5 (0.47) | RAB9AALDH1A1TDP1LMNA | |
| SCHEMBL19534376 | 0.81 | ADAMTS5 (0.47) | RAB9AALDH1A1TDP1LMNA | |
| SCHEMBL21046309 | 0.78 | — | — | |
| SCHEMBL21046310 | 0.78 | — | — | |
| SCHEMBL21046311 | 0.78 | — | — | |
| SCHEMBL254900 | 0.78 | ANPEP (0.39) | RAB9A | |
| SCHEMBL19534372 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4286001-A2 | BENZOYLGLYCINE DERIVATIVES AND METHODS OF MAKING AND USING SAME | Duke University (US) | 2023-12-06 | — | — | EP | disclosed |
| US-20210206715-A1 | Benzoylglycine Derivatives and Methods of Making and Using Same | DUKE UNIVERSITY (US) | 2021-07-08 | — | — | US | disclosed |
| US-11034649-B2 | Benzoylglycine derivatives and methods of making and using same | DUKE UNIVERSITY (US) | 2021-06-15 | — | — | US | disclosed |
| US-10550074-B2 | Benzoylglycine derivatives and methods of making and using same | DUKE UNIVERSITY (US) | 2020-02-04 | — | — | US | disclosed |
| US-20190169114-A1 | Benzoylglycine Derivatives and Methods of Making and Using Same | DUKE UNIVERSITY | 2019-06-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210206715-A1 | Benzoylglycine Derivatives and Methods of Making and Using Same | B3GAT3, GLO1, GLMN | AOC2 1902/4885MAPT 4583/4885RAB9A 1659/4885 |
| US-11034649-B2 | Benzoylglycine derivatives and methods of making and using same | B3GAT3, GLO1, GLMN | AOC2 1902/4885MAPT 4583/4885RAB9A 1659/4885 |
| US-20190169114-A1 | Benzoylglycine Derivatives and Methods of Making and Using Same | B3GAT3, GLO1, GLMN | AOC2 1902/4885MAPT 4583/4885RAB9A 1659/4885 |
| US-10550074-B2 | Benzoylglycine derivatives and methods of making and using same | B3GAT3, GLO1, GLMN | AOC2 1902/4885MAPT 4583/4885RAB9A 1659/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.