Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 5/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | TP53 | P04637 | 3/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | KCNJ6 | P48051 | 1/20 | 0.49 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.49 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19538023 | 0.78 | ALDH1A1 (0.59) | POLBALDH1A1TP53TSHRHPGD | |
| SCHEMBL20915691 | 0.78 | KDM4E (0.56) | POLBALDH1A1TP53TSHRHPGD | |
| SCHEMBL1061767 | 0.76 | KMT2A (0.72) | POLBALDH1A1TP53TSHRHPGD | |
| SCHEMBL20931185 | 0.75 | KDM4E (0.59) | POLBALDH1A1TP53TSHRKDM4E | |
| SCHEMBL8215669 | 0.74 | HPGD (0.70) | POLBALDH1A1TP53TSHRHPGD | |
| SCHEMBL3282703 | 0.73 | MEN1 (0.72) | POLBALDH1A1TP53TSHRHPGD | |
| SCHEMBL19784943 | 0.73 | DDX3X (0.77) | POLBKDM4EKMT2ACTDSP1SMN1; SMN2 | |
| SCHEMBL4024534 | 0.72 | HPGD (0.76) | POLBALDH1A1HPGDKMT2AL3MBTL1 | |
| SCHEMBL19520629 | 0.72 | GAA (0.57) | POLBALDH1A1TP53TSHRHPGD | |
| SCHEMBL19538198 | 0.71 | TP53 (0.66) | POLBALDH1A1TP53TSHRHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109153655-B | Novel N-acylurea derivatives and compositions comprising the same for preventing or treating cardiovascular diseases | 高丽大学校产学协力团 | 2022-09-30 | — | — | CN | claimed |
| CN-109153655-B | Novel N-acylurea derivatives and compositions comprising the same for preventing or treating cardiovascular diseases | 高丽大学校产学协力团 | 2022-09-30 | — | — | CN | disclosed |
| US-20220194928-A1 | NOVEL N-ACYLUREA DERIVATIVE AND COMPOSITION COMPRISING SAME FOR PREVENTION OR TREATMENT OF CARDIOVASCULAR DISEASE | UNIV KOREA RES & BUS FOUND (KR) | 2022-06-23 | — | — | US | disclosed |
| US-11306073-B2 | N-acylurea derivative and composition comprising same for prevention or treatment of cardiovascular disease | KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION (KR) | 2022-04-19 | — | — | US | disclosed |
| US-20190119261-A1 | NOVEL N-ACYLUREA DERIVATIVE AND COMPOSITION COMPRISING SAME FOR PREVENTION OR TREATMENT OF CARDIOVASCULAR DISEASE | KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION (KR) | 2019-04-25 | — | — | US | disclosed |
| WO-2017188551-A1 | NOVEL N-ACYLUREA DERIVATIVE AND COMPOSITION COMPRISING SAME FOR PREVENTION OR TREATMENT OF CARDIOVASCULAR DISEASE | 고려대학교산학협력단 | 2017-11-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190119261-A1 | NOVEL N-ACYLUREA DERIVATIVE AND COMPOSITION COMPRISING SAME FOR PREVENTION OR TREATMENT OF CARDIOVASCULAR DISEASE | TLN1, TNNI3, PTK2 | POLB 4514/4885ALDH1A1 2072/4885TP53 4267/4885 |
| US-20220194928-A1 | NOVEL N-ACYLUREA DERIVATIVE AND COMPOSITION COMPRISING SAME FOR PREVENTION OR TREATMENT OF CARDIOVASCULAR DISEASE | TLN1, TNNI3, PTK2 | POLB 4514/4885ALDH1A1 2072/4885TP53 4267/4885 |
| US-11306073-B2 | N-acylurea derivative and composition comprising same for prevention or treatment of cardiovascular disease | TLN1, PTK2, TNNI3 | POLB 4459/4885ALDH1A1 1910/4885TP53 4197/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.