Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 2/20 | 0.48 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | PLK1 | P53350 | 1/20 | 0.46 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.46 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | PCNA | P12004 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16015432 | 0.90 | MAPT (0.48) | MTNR1AMTNR1BFFAR1HPGDGAA | |
| SCHEMBL14233695 | 0.86 | HPGD (0.54) | MTNR1AMTNR1BHPGDGAAMAPT | |
| SCHEMBL23866994 | 0.85 | CYP4F2 (0.46) | MTNR1AMTNR1BFFAR1HPGDGAA | |
| SCHEMBL19182347 | 0.85 | FFAR1 (0.49) | MTNR1AMTNR1BFFAR1HPGDGAA | |
| SCHEMBL20109375 | 0.85 | FFAR1 (0.46) | MTNR1AMTNR1BFFAR1GAAMAPT | |
| SCHEMBL14724832 | 0.83 | MEN1 (0.53) | FFAR1GAAMAPTHDAC3ALDH1A1 | |
| SCHEMBL14234254 | 0.82 | HPGD (0.43) | MTNR1AMTNR1BHPGDGAAMAPT | |
| SCHEMBL21103820 | 0.82 | HDAC2 (0.45) | MTNR1AMTNR1BFFAR1GAAMAPT | |
| SCHEMBL19541311 | 0.82 | FFAR1 (0.42) | MTNR1AMTNR1BFFAR1HPGDGAA | |
| SCHEMBL30559640 | 0.81 | TAAR1 (0.57) | FFAR1GAAMAPTALDH1A1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017190107-A1 | SIGMA RECEPTOR BINDERS | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2017-11-02 | — | — | WO | disclosed |