Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | PCNA | P12004 | 1/20 | 0.45 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.45 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.41 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.41 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19182347 | 0.90 | FFAR1 (0.49) | FFAR1MAPTGAAPCNACYP4F2 | |
| SCHEMBL19540907 | 0.85 | MTNR1A (0.48) | FFAR1MAPTGAAPCNACYP4F2 | |
| SCHEMBL16015432 | 0.85 | MAPT (0.48) | FFAR1MAPTGAAPCNACYP4F2 | |
| SCHEMBL19176009 | 0.81 | FFAR1 (0.45) | FFAR1MAPTGAAPCNACYP4F2 | |
| SCHEMBL14724832 | 0.81 | MEN1 (0.53) | FFAR1MAPTGAAALDH1A1HDAC2 | |
| SCHEMBL23866994 | 0.81 | CYP4F2 (0.46) | FFAR1MAPTGAAPCNACYP4F2 | |
| SCHEMBL21103820 | 0.81 | HDAC2 (0.45) | FFAR1MAPTGAAPCNACYP4F2 | |
| SCHEMBL14548815 | 0.80 | MAOA (0.50) | FFAR1MAPTGAAPCNACYP4F2 | |
| SCHEMBL30559640 | 0.80 | TAAR1 (0.57) | FFAR1MAPTGAAALDH1A1HDAC2 | |
| SCHEMBL3295184 | 0.80 | SIRT2 (0.51) | MAPTCYP4F2CYP4A11ALDH1A1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2534152-B1 | MACROCYCLES AS FACTOR XIA INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2018-05-02 | — | — | EP | disclosed |