Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 1/20 | 0.46 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.40 |
| ▸ | PCNA | P12004 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.40 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19287558 | 0.86 | RAB9A (0.43) | NPC1RAB9AGAAMAPTALDH1A1 | |
| SCHEMBL19540907 | 0.85 | MTNR1A (0.48) | CYP4F2CYP4A11FFAR1GAAMAPT | |
| SCHEMBL16015432 | 0.82 | MAPT (0.48) | CYP4F2CYP4A11FFAR1GAAMAPT | |
| SCHEMBL12993335 | 0.81 | CYP2C19 (0.46) | CYP4F2CYP4A11FFAR1NPC1RAB9A | |
| SCHEMBL23866985 | 0.81 | SIRT2 (0.49) | CYP4F2CYP4A11ALDH1A1KDM4E | |
| SCHEMBL20109375 | 0.81 | FFAR1 (0.46) | CYP4F2CYP4A11FFAR1RAB9AGAA | |
| SCHEMBL14548815 | 0.81 | MAOA (0.50) | CYP4F2CYP4A11FFAR1GAAMAPT | |
| SCHEMBL19182347 | 0.81 | FFAR1 (0.49) | CYP4F2CYP4A11FFAR1RAB9AGAA | |
| SCHEMBL14724832 | 0.79 | MEN1 (0.53) | FFAR1NPC1RAB9AGAAMAPT | |
| SCHEMBL21103820 | 0.78 | HDAC2 (0.45) | CYP4F2CYP4A11FFAR1RAB9AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210300903-A1 | SIGMA RECEPTOR BINDERS | UNIV TEXAS (US) | 2021-09-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210300903-A1 | SIGMA RECEPTOR BINDERS | SIGMAR1, OPRK1, OPRL1 | CYP4F2 3855/4885CYP4A11 3291/4885FFAR1 178/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.