SCHEMBL19543

SCHEMBL19543

COC(=O)c1ccc(C(=O)Cl)cc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 3/20 0.64
CA2 P00918 3/20 0.64
CA12 O43570 2/20 0.64
CA7 P43166 2/20 0.64
CA9 Q16790 2/20 0.64
CA14 Q9ULX7 2/20 0.64
TDP1 Q9NUW8 1/20 0.64
TSHR P16473 1/20 0.60
MAPT P10636 6/20 0.57
ALDH1A1 P00352 2/20 0.57
LOXL2 Q9Y4K0 1/20 0.55
MEN1 O00255 3/20 0.53
KMT2A Q03164 3/20 0.53
XDH P47989 1/20 0.52
RAB9A P51151 2/20 0.52
CASP3 P42574 1/20 0.52
SENP8 Q96LD8 1/20 0.52
SENP7 Q9BQF6 1/20 0.52
SENP6 Q9GZR1 1/20 0.52
L3MBTL1 Q9Y468 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethylenediamine SCHEMBL8996794 0.90 LOXL2 (0.61) CA1CA2CA12CA7CA9
SCHEMBL28993944 0.87 CA1 (0.80) CA1CA2CA12CA7CA9
SCHEMBL23600 0.87 CA1 (0.80) CA1CA2CA12CA7CA9
SCHEMBL27846423 0.85 NPC1 (0.71) TSHRMAPTALDH1A1MEN1KMT2A
Methyl Alcohol SCHEMBL28561085 0.85 CA1 (0.76) CA1CA2CA12CA7CA9
SCHEMBL28993277 0.85 CA1 (0.76) CA1CA2CA12CA7CA9
SCHEMBL28704033 0.85 CA1 (0.76) CA1CA2CA12CA7CA9
SCHEMBL28531063 0.85 CA1 (0.76) CA1CA2CA12CA7CA9
Water SCHEMBL22720573 0.85 CA1 (0.76) CA1CA2CA12CA7CA9
Ammonia Solution, Strong SCHEMBL28873355 0.85 CA1 (0.76) CA1CA2CA12CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1376 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117285437-B Bexarotene derivative, preparation method and application thereof, and anti-tumor drug 沈阳药科大学 2024-09-17 CN claimed
CN-118307497-A Terephthalamide antitumor compound and preparation method and application thereof 江苏海洋大学 2024-07-09 CN claimed
CN-117285437-A Bexarotene derivative, preparation method and application thereof, and anti-tumor drug 沈阳药科大学 2023-12-26 CN claimed
CN-114230495-B Hydrogenated nitrosyl donor and preparation method thereof 海南大学 2023-01-06 CN claimed
CN-114230495-A Hydrogenated nitrosyl donor and preparation method thereof 海南大学 2022-03-25 CN claimed
CN-114195731-A Hydrogenated nitrosyl donor compound and preparation method thereof 海南大学 2022-03-18 CN claimed
CN-110872344-B Chloramphenicol complete antigen and preparation method and application thereof 中国农业大学 2021-07-16 CN claimed
CN-110683974-B Thioether compound, synthesis method thereof and application thereof in polypeptide cyclization 厦门大学 2020-07-31 CN claimed
CN-111454180-A Somalutide side chain intermediate and preparation method thereof 大连阿拉宁生物技术有限公司 2020-07-28 CN claimed
CN-108440389-B 3,4, 5-trihydroxybenzoic acid derivative and preparation method and application thereof 山东大学 2020-05-29 CN claimed
CN-110683974-A Thioether compound, synthesis method thereof and application thereof in polypeptide cyclization 厦门大学 2020-01-14 CN claimed
CN-108440389-A 3,4,5-trihydroxy benzoic acid derivative and the preparation method and application thereof 山东大学 2018-08-24 CN claimed
CN-103785130-A Fire extinguishing composition containing carboxylic acid derivatives XI AN JIAN RUI SAFETY EMERGENCY EQUIPMENT LTD LIABILITY COMPANY 2014-05-14 CN claimed
CN-100427457-C Method for preparing p-aminobenzoic acid SK CHEMICALS CO LTD (KR) 2008-10-22 CN claimed
CN-1709858-A 4-amino-6-nitro resorcin hydrochloride, and its preparation and use UNIV ZHEJIANG POLYTECHNIC (CN) 2005-12-21 CN claimed
CN-1625545-A Preparation method of p-aminobenzoic acid SK CHEMICALS CO LTD (KR) 2005-06-08 CN claimed
WO-2003072534-A1 METHOD FOR PREPARING P-AMINOBENZOIC ACID SK CHEMICALS CO., LTD. (KR) 2003-09-04 WO claimed
WO-1993014055-A1 PREPARATION OF 2,5-DICHLOROBENZOPHENONES MAXDEM INCORPORATED (US) 1993-07-22 WO claimed
US-5210313-A Friedel crafts aryloylation of 1,4-dichlorobenzene and Lewis acids MAXDEM INCORPORATED (US) 1993-05-11 US claimed
EP-0125195-B1 4'-FLAVONECARBOXYLIC ACIDS, PROCESS FOR THEIR PREPARATION AND THEIR THERAPEUTICAL USE CORTIAL S.A. (FR) 1987-09-30 EP claimed