Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D
The experimentally established mechanism targets of Ethylenediamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.61 |
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | CA1 | P00915 | 3/20 | 0.53 |
| ▸ | CA2 | P00918 | 3/20 | 0.53 |
| ▸ | CA12 | O43570 | 2/20 | 0.53 |
| ▸ | CA9 | Q16790 | 2/20 | 0.53 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | CA7 | P43166 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.47 |
| ▸ | STS | P08842 | 1/20 | 0.47 |
| ▸ | DPP4 | P27487 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19543 | 0.90 | CA1 (0.64) | LOXL2MAPTCA1CA2CA12 | |
| SCHEMBL23600 | 0.78 | CA1 (0.80) | LOXL2MAPTCA1CA2CA12 | |
| SCHEMBL28993944 | 0.78 | CA1 (0.80) | LOXL2MAPTCA1CA2CA12 | |
| SCHEMBL443043 | 0.78 | MAPT (0.79) | LOXL2MAPTCA1CA2TDP1 | |
| SCHEMBL230590 | 0.77 | LOXL2 (0.72) | LOXL2MAPTCA1CA2CA12 | |
| Urea SCHEMBL20838278 | 0.77 | CA1 (0.70) | LOXL2MAPTCA1CA2CA12 | |
| Hydrochloric Acid SCHEMBL442778 | 0.77 | MAPT (0.77) | LOXL2MAPTCA1CA2TDP1 | |
| SCHEMBL27846423 | 0.77 | NPC1 (0.71) | MAPTTSHRMEN1KMT2ARAB9A | |
| SCHEMBL8683825 | 0.77 | MAPT (0.77) | LOXL2MAPTCA1CA2TDP1 | |
| Water SCHEMBL22720573 | 0.76 | CA1 (0.76) | LOXL2MAPTCA1CA2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0724568-A1 | AMIDO PEROXYCARBOXYLIC ACIDS FOR BLEACHING | UNILEVER PLC (GB) | 1996-08-07 | — | — | EP | disclosed |
| WO-1995003275-A1 | AMIDO PEROXYCARBOXYLIC ACIDS FOR BLEACHING | UNILEVER N.V. (NL) | 1995-02-02 | — | — | WO | disclosed |