Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 8/20 | 0.56 |
| ▸ | CYP11B1 | P15538 | 7/20 | 0.56 |
| ▸ | CYP19A1 | P11511 | 6/20 | 0.56 |
| ▸ | CYP17A1 | P05093 | 4/20 | 0.56 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.43 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.43 |
| ▸ | DHODH | Q02127 | 1/20 | 0.43 |
| ▸ | KMO | O15229 | 1/20 | 0.43 |
| ▸ | FHIT | P49789 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.41 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24403785 | 0.89 | CYP11B2 (0.50) | CYP11B2CYP11B1CYP19A1CYP17A1CYP2A6 | |
| SCHEMBL10032431 | 0.89 | CYP11B2 (0.70) | CYP11B2CYP11B1CYP19A1CYP17A1CYP2A6 | |
| SCHEMBL19009621 | 0.88 | CYP11B2 (0.49) | CYP11B2CYP11B1CYP19A1CYP17A1CYP2A6 | |
| SCHEMBL19009625 | 0.86 | CYP11B2 (0.58) | CYP11B2CYP11B1CYP19A1CYP17A1CYP2A6 | |
| SCHEMBL17320786 | 0.86 | CYP11B1 (0.46) | CYP11B2CYP11B1CYP19A1CYP17A1CYP2A6 | |
| SCHEMBL13016367 | 0.86 | CYP11B2 (0.57) | CYP11B2CYP11B1CYP19A1CYP17A1CYP2A6 | |
| SCHEMBL13015741 | 0.85 | CYP11B2 (0.68) | CYP11B2CYP11B1CYP19A1CYP17A1CYP2A6 | |
| SCHEMBL9973738 | 0.85 | CYP2A6 (0.58) | CYP11B1CYP19A1CYP2A6KMOFHIT | |
| SCHEMBL10032221 | 0.82 | CYP11B2 (0.73) | CYP11B2CYP11B1CYP19A1CYP17A1CYP2A6 | |
| SCHEMBL15977568 | 0.82 | CYP1A1 (0.42) | CYP11B2CYP11B1CYP19A1CYP17A1PIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170317294-A1 | ORGANIC LIGHT-EMITTING DEVICE | SAMSUNG DISPLAY CO., LTD. (KR) | 2017-11-02 | — | — | US | disclosed |