SCHEMBL19543762

SCHEMBL19543762

c1ccc(-c2ccc3oc4ccc(-c5ccc6cc(N(c7ccccc7)c7ccccc7)ccc6c5)cc4c3c2)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PGR P06401 2/20 0.45
PLA2G2A P14555 3/20 0.41
PLA2G4A P47712 3/20 0.41
ESR1 P03372 3/20 0.40
ESR2 Q92731 3/20 0.40
PRKDC P78527 3/20 0.39
GAA P10253 2/20 0.38
L3MBTL1 Q9Y468 2/20 0.38
CASP3 P42574 1/20 0.36
SENP7 Q9BQF6 1/20 0.36
SENP6 Q9GZR1 1/20 0.36
BACE1 P56817 1/20 0.36
PLA2G10 O15496 1/20 0.36
TBK1 Q9UHD2 1/20 0.36
ANO1 Q5XXA6 1/20 0.35
KDM4E B2RXH2 2/20 0.35
MAPT P10636 2/20 0.35
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
GLA P06280 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19103162 0.97 PGR (0.43) PGRPLA2G2APLA2G4AESR1ESR2
SCHEMBL19103160 0.97 PGR (0.43) PGRPLA2G2APLA2G4AESR1ESR2
SCHEMBL16639233 0.94 PGR (0.39) PGRPLA2G2APLA2G4AESR1ESR2
SCHEMBL17886267 0.93 PLA2G2A (0.42) PGRPLA2G2APLA2G4AESR1ESR2
SCHEMBL21249848 0.93 PLA2G2A (0.42) PGRPLA2G2APLA2G4AESR1ESR2
SCHEMBL27274452 0.93 PLA2G2A (0.42) PGRPLA2G2APLA2G4AESR1ESR2
SCHEMBL27274447 0.93 PLA2G2A (0.42) PGRPLA2G2APLA2G4AESR1ESR2
SCHEMBL17703028 0.93 PGR (0.39) PGRPLA2G2APLA2G4AESR1ESR2
SCHEMBL27272433 0.93 PGR (0.42) PGRPLA2G2APLA2G4AESR1ESR2
SCHEMBL14902184 0.93 PLA2G2A (0.44) PGRPLA2G2APLA2G4AESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170317294-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2017-11-02 US disclosed