SCHEMBL195532

SCHEMBL195532

O=C(O)C(c1ccccc1)C(F)(F)F

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SRC P12931 2/20 0.50
CYP2D6 P10635 1/20 0.50
LMNA P02545 2/20 0.48
MAPK1 P28482 1/20 0.48
L3MBTL1 Q9Y468 2/20 0.43
ATM Q13315 1/20 0.43
CES1 P23141 2/20 0.41
CES2 O00748 1/20 0.41
PDPK1 O15530 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
ACP3 P15309 1/20 0.39
HDAC3 O15379 1/20 0.39
HDAC4 P56524 1/20 0.39
HDAC1 Q13547 1/20 0.39
HDAC7 Q8WUI4 1/20 0.39
HDAC2 Q92769 1/20 0.39
HDAC10 Q969S8 1/20 0.39
HDAC11 Q96DB2 1/20 0.39
HDAC8 Q9BY41 1/20 0.39
HDAC6 Q9UBN7 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4026079 1.00 SRC (0.50) SRCCYP2D6LMNAMAPK1L3MBTL1
SCHEMBL7955519 1.00 SRC (0.50) SRCCYP2D6LMNAMAPK1L3MBTL1
Hydrochloric Acid SCHEMBL2529822 0.98 SRC (0.48) SRCCYP2D6LMNAMAPK1L3MBTL1
SCHEMBL29773675 0.98 SRC (0.48) SRCCYP2D6LMNAMAPK1L3MBTL1
Methyl Alcohol SCHEMBL5139174 0.96 SRC (0.46) SRCCYP2D6LMNAMAPK1L3MBTL1
SCHEMBL28044484 0.86 CYP2D6 (0.44) SRCCYP2D6LMNAMAPK1L3MBTL1
SCHEMBL6971672 0.84 CYP2D6 (0.43) SRCCYP2D6LMNAMAPK1L3MBTL1
SCHEMBL1483540 0.84 EPHX1 (0.46) SRCCYP2D6LMNAMAPK1L3MBTL1
SCHEMBL3435446 0.83 PTPN5 (0.46) SRCCYP2D6HDAC4
SCHEMBL11034663 0.83 ESR1 (0.56) SRCL3MBTL1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 321 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025110550-A1 COMPLEX FOR GENE DELIVERY 전남대학교산학협력단 2025-05-30 WO claimed
CN-119977814-A Compound AX-Bn with metabolic activity improving function and preparation method thereof 生命奇观(苏州)生物科技有限公司 2025-05-13 CN claimed
CN-119486565-A Perovskite precursor solution, perovskite solar cell, preparation method and photovoltaic module 天合光能股份有限公司 2025-02-18 CN claimed
CN-118184679-A Photothermal agent and preparation method thereof, photothermal nanoparticle and preparation method thereof, insulating material and self-repairing method of insulating material 中国石油天然气股份有限公司 2024-06-14 CN claimed
CN-117105931-A Method for preparing pyridopyrimidine compounds and intermediate thereof 上海翰森生物医药科技有限公司 2023-11-24 CN claimed
CN-115872857-A Netupitant key impurity and preparation method thereof 四川科伦药物研究院有限公司 2023-03-31 CN claimed
CN-115784961-A Synthesis method of oxacillin and intermediate thereof 上海鼎雅药物化学科技有限公司 2023-03-14 CN claimed
CN-115215879-A 3-aryl-4, 5-pyranocoumarin derivatives, and preparation method and application thereof 广西中医药大学 2022-10-21 CN claimed
CN-109219601-B Method for preparing optically active beraprost 奇诺因药物和化学工厂私人有限公司 2022-08-09 CN claimed
WO-2021215852-A1 PHARMACEUTICAL COMPOSITION FOR TREATMENT OF HYPERTROPHIC CARDIOMYOPATHY AND TREATMENT METHOD USING SAME COMPOSITION (주)셀트리온 (KR) 2021-10-28 WO claimed
CN-108684983-A A kind of training algae fertilizer containing Chinese herbal medicine 金华市呗力水产养殖技术有限公司 2018-10-23 CN claimed
CN-108218753-A A kind of preparation method of 2- (4- trifluoromethyl benzyls) pyrrolidines 湖南华腾制药有限公司 2018-06-29 CN claimed
CN-104892456-A Method for preparing benzonitrile compound UNIV HUNAN 2015-09-09 CN claimed
WO-2010121226-A2 ANTICANCER AGENTS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2010-10-21 WO claimed
CN-101544561-A Preparation method of trifluoromethyl phenylacetic acid UNIV JIANGSU POLYTECHNIC 2009-09-30 CN claimed
EP-1458701-A1 METHOD FOR THE PREPARATION OF ESCITALOPRAM H. Lundbeck A/S (DK) 2004-09-22 EP claimed
CN-1163619-C Method and compositions for determining sequence of nucleic acid molecules �Ѹ�������ѧ��˾ 2004-08-25 CN claimed
WO-2003051861-A1 METHOD FOR THE PREPARATION OF ESCITALOPRAM H. LUNDBECK A/S (DK) 2003-06-26 WO claimed
CN-1212021-A Method and compositions for determining sequence of nucleic acid molecules RAPIGENE INC (US) 1999-03-24 CN claimed
EP-0493048-A1 The process for the preparation of enantiomerically pure thienopyran derivative ORTHO PHARMACEUTICAL CORPORATION (US) 1992-07-01 EP claimed