Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | RARA | P10276 | 4/20 | 0.49 |
| ▸ | RARB | P10826 | 4/20 | 0.49 |
| ▸ | RARG | P13631 | 4/20 | 0.49 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.48 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.47 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.47 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.47 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 5/20 | 0.41 |
| ▸ | AKR1C2 | P52895 | 5/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8081677 | 0.85 | KDM4E (0.55) | KDM4ERARARARBRARGMRGPRX4 | |
| SCHEMBL11468438 | 0.84 | KDM4E (0.46) | KDM4ERARARARBRARGMRGPRX4 | |
| SCHEMBL7907125 | 0.82 | RARB (0.54) | KDM4ERARARARBRARGGRIN2D | |
| SCHEMBL11463895 | 0.81 | AKR1C3 (0.63) | KDM4ERARARARBRARGAKR1C3 | |
| SCHEMBL20178615 | 0.81 | KDM4E (0.51) | KDM4ERARARARBRARGGRIN2D | |
| SCHEMBL18758 | 0.81 | KDM4E (0.68) | KDM4ERARARARBRARGGRIN2D | |
| SCHEMBL29594563 | 0.81 | KDM4E (0.68) | KDM4ERARARARBRARGGRIN2D | |
| SCHEMBL29359975 | 0.81 | KDM4E (0.68) | KDM4ERARARARBRARGGRIN2D | |
| SCHEMBL6916181 | 0.81 | KDM4E (0.68) | KDM4ERARARARBRARGGRIN2D | |
| SCHEMBL19774287 | 0.80 | KDM4E (0.50) | KDM4ERARARARBRARGGRIN2D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017192304-A1 | ARYLCARBOXAMIDES AND USES THEREOF | INCEPTION 1, INC. (US) | 2017-11-09 | — | — | WO | disclosed |