Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.57 |
| ▸ | ABL1 | P00519 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | RORC | P51449 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | CASP7 | P55210 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CFTR | P13569 | 3/20 | 0.41 |
| ▸ | ULK1 | O75385 | 1/20 | 0.41 |
| ▸ | NQO2 | P16083 | 2/20 | 0.40 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22987085 | 0.88 | GAA (0.72) | GAAKDM4EABL1HTTALDH1A1 | |
| SCHEMBL2617488 | 0.88 | GAA (0.44) | GAAKDM4EABL1RORCALDH1A1 | |
| SCHEMBL2617486 | 0.84 | ALDH1A1 (0.48) | GAAKDM4ERORCALDH1A1HPGD | |
| SCHEMBL2617461 | 0.84 | GAA (0.41) | GAAKDM4EABL1RORCCSNK2A1 | |
| SCHEMBL7853424 | 0.84 | GAA (0.76) | GAAKDM4EABL1HTTALDH1A1 | |
| SCHEMBL3661787 | 0.83 | HTT (0.46) | GAAABL1HTTRORCHPGD | |
| SCHEMBL2857865 | 0.83 | KDM4E (0.78) | GAAKDM4EABL1HTTALDH1A1 | |
| SCHEMBL1786323 | 0.82 | GAA (0.51) | GAAKDM4EABL1HTTRORC | |
| SCHEMBL1884944 | 0.80 | GAA (0.64) | GAAKDM4EABL1HTTALDH1A1 | |
| SCHEMBL8066375 | 0.79 | RORC (0.44) | GAAKDM4EHTTRORCALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017192304-A1 | ARYLCARBOXAMIDES AND USES THEREOF | INCEPTION 1, INC. (US) | 2017-11-09 | — | — | WO | disclosed |