Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 7/20 | 0.53 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.53 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 4/20 | 0.50 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | RXRA | P19793 | 1/20 | 0.50 |
| ▸ | RXRB | P28702 | 1/20 | 0.50 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.50 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.50 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | MITF | O75030 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | XBP1 | P17861 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9550355 | 0.89 | FOLH1 (0.55) | MRGPRX4PTGER1FOLH1HPGDMCL1 | |
| SCHEMBL383618 | 0.87 | FOLH1 (0.58) | MRGPRX4PTGER1FOLH1HPGDMCL1 | |
| SCHEMBL20535507 | 0.83 | GAA (0.51) | MRGPRX4HPGDNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL12659905 | 0.83 | MCL1 (0.60) | MRGPRX4PTGER1FOLH1HPGDMCL1 | |
| SCHEMBL16432058 | 0.83 | FOLH1 (0.55) | PTGER1FOLH1MCL1RAB9ASMN1; SMN2 | |
| SCHEMBL30261516 | 0.83 | MRGPRX4 (0.60) | MRGPRX4PTGER1FOLH1HPGDMCL1 | |
| SCHEMBL3138320 | 0.82 | CTSV (0.57) | MRGPRX4FOLH1HPGDNPC1RAB9A | |
| SCHEMBL4728946 | 0.82 | CTSV (0.57) | MRGPRX4FOLH1HPGDNPC1RAB9A | |
| SCHEMBL7797930 | 0.82 | MRGPRX4 (0.61) | MRGPRX4PTGER1FOLH1HPGDMCL1 | |
| SCHEMBL2565901 | 0.82 | GAA (0.50) | MRGPRX4HPGDNPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017192304-A1 | ARYLCARBOXAMIDES AND USES THEREOF | INCEPTION 1, INC. (US) | 2017-11-09 | — | — | WO | disclosed |