Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 1/20 | 0.55 |
| ▸ | PTGER1 | P34995 | 3/20 | 0.53 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | RXRA | P19793 | 1/20 | 0.50 |
| ▸ | RXRB | P28702 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.50 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.50 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | MITF | O75030 | 1/20 | 0.50 |
| ▸ | XBP1 | P17861 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9550346 | 0.89 | RXRA (0.56) | PTGER1HPGDTP53RXRARXRB | |
| SCHEMBL19554264 | 0.89 | MRGPRX4 (0.53) | FOLH1PTGER1MCL1HPGDTP53 | |
| SCHEMBL9550479 | 0.87 | NPC1 (0.47) | FOLH1HPGDTP53MEN1NPC1 | |
| SCHEMBL383618 | 0.87 | FOLH1 (0.58) | FOLH1PTGER1MCL1HPGDTP53 | |
| SCHEMBL10089235 | 0.83 | FOLH1 (0.69) | FOLH1PTGER1MCL1KDM4EALDH1A1 | |
| SCHEMBL20400911 | 0.83 | FOLH1 (0.55) | FOLH1PTGER1MCL1KDM4EALDH1A1 | |
| SCHEMBL21327232 | 0.82 | MRGPRX4 (0.61) | FOLH1PTGER1MCL1HPGDRXRA | |
| SCHEMBL2565901 | 0.82 | GAA (0.50) | HPGDTP53RXRARXRBKDM4E | |
| SCHEMBL28173965 | 0.81 | FOLH1 (0.56) | FOLH1PTGER1MCL1KDM4EALDH1A1 | |
| SCHEMBL16432058 | 0.80 | FOLH1 (0.55) | FOLH1PTGER1MCL1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5236931-A | Treating anxiety, psychosis, cognitive dysfunction, migrane, cluster headache, trigeminal neuralgia emesis and impaired gastric motility | A. H. ROBINS COMPANY, INCORPORATED (US) | 1993-08-17 | — | — | US | disclosed |