Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 4/20 | 0.43 |
| ▸ | CFTR | P13569 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19554272 | 0.88 | LMNA (0.55) | KDM4ELMNAGAACFTRALDH1A1 | |
| SCHEMBL16410988 | 0.84 | KDM4E (0.68) | KDM4ELMNAGAACFTRALDH1A1 | |
| SCHEMBL31716930 | 0.80 | KDM4E (0.76) | KDM4EGAACFTRALDH1A1HPGD | |
| SCHEMBL19554334 | 0.80 | KDM4E (0.53) | KDM4ELMNAGAAALDH1A1HPGD | |
| SCHEMBL1567762 | 0.79 | KDM4E (0.54) | KDM4ELMNAGAACFTRALDH1A1 | |
| SCHEMBL16411016 | 0.79 | KDM4E (0.50) | KDM4ELMNAGAACFTRALDH1A1 | |
| SCHEMBL24761763 | 0.78 | KDM4E (0.53) | KDM4ELMNAGAACFTRALDH1A1 | |
| SCHEMBL19554322 | 0.78 | KDM4E (0.48) | KDM4ELMNAGAACFTRALDH1A1 | |
| SCHEMBL22073608 | 0.77 | KDM4E (0.38) | KDM4ELMNAGAAALDH1A1HPGD | |
| SCHEMBL3618785 | 0.77 | GAA (0.52) | KDM4ELMNAGAACFTRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017192304-A1 | ARYLCARBOXAMIDES AND USES THEREOF | INCEPTION 1, INC. (US) | 2017-11-09 | — | — | WO | disclosed |