Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 5/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | HPGD | P15428 | 4/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | XDH | P47989 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19554261 | 0.86 | XDH (0.46) | KDM4EHSD17B10ALDH1A1HPGDTSHR | |
| SCHEMBL16410988 | 0.85 | KDM4E (0.68) | KDM4EMAPTRXFP1HSD17B10GAA | |
| SCHEMBL19554301 | 0.84 | KDM4E (0.48) | KDM4EMAPTRXFP1HSD17B10GAA | |
| SCHEMBL6384036 | 0.84 | KDM4E (0.69) | KDM4EMAPTHSD17B10GAATDP1 | |
| SCHEMBL30988420 | 0.81 | KDM4E (0.43) | KDM4EMAPTRXFP1HSD17B10GAA | |
| SCHEMBL27427356 | 0.81 | KDM4E (0.43) | KDM4EMAPTRXFP1HSD17B10GAA | |
| SCHEMBL19554272 | 0.81 | LMNA (0.55) | KDM4EMAPTRXFP1HSD17B10GAA | |
| SCHEMBL1567762 | 0.81 | KDM4E (0.54) | KDM4EMAPTRXFP1HSD17B10GAA | |
| SCHEMBL18655513 | 0.80 | KDM4E (0.58) | KDM4EMAPTHSD17B10GAATDP1 | |
| SCHEMBL1012737 | 0.80 | KDM4E (0.78) | KDM4EMAPTHSD17B10GAATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017192304-A1 | ARYLCARBOXAMIDES AND USES THEREOF | INCEPTION 1, INC. (US) | 2017-11-09 | — | — | WO | disclosed |