Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | F10 | P00742 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 5/20 | 0.54 |
| ▸ | RAB9A | P51151 | 5/20 | 0.54 |
| ▸ | DHODH | Q02127 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 6/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.46 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18118626 | 0.81 | KDM4E (0.68) | GAAF10NPC1RAB9ADHODH | |
| SCHEMBL2889107 | 0.81 | GAA (0.55) | GAAF10NPC1RAB9ADHODH | |
| SCHEMBL28466857 | 0.79 | ALDH1A1 (0.70) | GAANPC1RAB9AMEN1KMT2A | |
| SCHEMBL1307456 | 0.78 | GRIK1 (0.67) | F10DHODHMEN1KMT2AKDM4E | |
| SCHEMBL3274273 | 0.75 | EGFR (0.51) | NPC1RAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL3274276 | 0.75 | EGFR (0.51) | NPC1RAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL3792756 | 0.74 | KIF11 (0.50) | SMN1; SMN2HPGDCCR2 | |
| SCHEMBL12218536 | 0.74 | NPC1 (0.72) | GAANPC1RAB9ADHODHMEN1 | |
| SCHEMBL13797933 | 0.74 | MAPK14 (0.68) | NPC1RAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL19575429 | 0.73 | F10 (0.53) | GAAF10NPC1RAB9ADHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017192304-A1 | ARYLCARBOXAMIDES AND USES THEREOF | INCEPTION 1, INC. (US) | 2017-11-09 | — | — | WO | claimed |
| WO-2017192304-A1 | ARYLCARBOXAMIDES AND USES THEREOF | INCEPTION 1, INC. (US) | 2017-11-09 | — | — | WO | disclosed |
| WO-2017192304-A1 | ARYLCARBOXAMIDES AND USES THEREOF | INCEPTION 1, INC. (US) | 2017-11-09 | — | — | WO | disclosed |