Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MMP9 | P14780 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | PRKCA | P17252 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10332206 | 0.85 | ALDH1A1 (0.39) | ALDH1A1 | |
| SCHEMBL7143399 | 0.85 | ALDH1A1 (0.39) | ALDH1A1MAPTMAPK1 | |
| SCHEMBL7149596 | 0.85 | ALDH1A1 (0.39) | ALDH1A1MAPTMAPK1 | |
| SCHEMBL7045383 | 0.82 | ALDH1A1 (0.36) | ALDH1A1LMNAPRKCA | |
| SCHEMBL7045377 | 0.82 | ALDH1A1 (0.36) | ALDH1A1LMNAPRKCA | |
| SCHEMBL17183874 | 0.78 | ALDH1A1 (0.46) | ALDH1A1USP2TSHRTP53KDM4E | |
| SCHEMBL6650690 | 0.78 | ALDH1A1 (0.46) | ALDH1A1USP2TSHRTP53KDM4E | |
| SCHEMBL19506424 | 0.76 | — | — | |
| SCHEMBL18216669 | 0.76 | — | — | |
| SCHEMBL5049326 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-60105650-A | — | — | None | — | — | JP | disclosed |
| US-9617453-B2 | Solvent free aqueous polyurethane dispersions and methods of making and using the same | AIR PRODUCTS AND CHEMICALS, INC. (US) | 2017-04-11 | — | — | US | disclosed |
| US-20110306724-A1 | Solvent Free Aqueous Polyurethane Dispersions and Methods of Making and Using the Same | AIR PRODUCTS AND CHEMICALS, INC. (US) | 2011-12-15 | — | — | US | disclosed |
| EP-2332998-A1 | Solvent free aqueous polyurethane dispersions and methods of making and using the same | Air Products and Chemicals, Inc. (US) | 2011-06-15 | — | — | EP | disclosed |
| US-5270433-A | Polyurethane-based universal household adhesive | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1993-12-14 | — | — | US | disclosed |
| JP-S60105650-A | GLYCEROL DERIVATIVE, PRODUCTION THEREOF AND PHARMACEUTICAL CONTAINING SAID DERIVATIVE | ONO PHARMACEUT CO LTD | 1985-06-11 | — | — | JP | disclosed |