Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MME | P08473 | 2/20 | 0.35 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | PRKCA | P17252 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7045383 | 1.00 | ALDH1A1 (0.36) | ALDH1A1SMN1; SMN2LMNAMMESLC22A6 | |
| SCHEMBL27627837 | 0.83 | ALDH1A1 (0.36) | ALDH1A1SMN1; SMN2LMNAMMESLC22A6 | |
| SCHEMBL1955477 | 0.82 | ALDH1A1 (0.46) | ALDH1A1LMNAPRKCA | |
| SCHEMBL28760186 | 0.79 | LMNA (0.56) | SMN1; SMN2LMNACYP1A2 | |
| SCHEMBL27528807 | 0.79 | LMNA (0.56) | SMN1; SMN2LMNACYP1A2 | |
| Hydrochloric Acid SCHEMBL8896645 | 0.77 | LMNA (0.59) | ALDH1A1SMN1; SMN2LMNACYP1A2 | |
| SCHEMBL4851581 | 0.77 | ENPEP (0.35) | ALDH1A1LMNASLC22A6CYP1A2 | |
| SCHEMBL4199095 | 0.76 | ALDH1A1 (0.34) | ALDH1A1SMN1; SMN2LMNAMME | |
| SCHEMBL6802604 | 0.74 | GPR84 (0.51) | LMNACYP1A2 | |
| SCHEMBL7149596 | 0.74 | ALDH1A1 (0.39) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0924206-B1 | Process for producing (R)-3-Hydroxy-4-Butyrolactone useful for preparing (R)-Carnitine | SIGMA TAU IND FARMACEUTI (IT) | 2003-04-02 | — | — | EP | disclosed |
| US-6127552-A | Process for producing (R)-3-hydroxy-4-butyrolactone useful for preparing (R)-carnitine | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) | 2000-10-03 | — | — | US | disclosed |
| EP-0924206-A1 | Process for producing (R)-3-Hydroxy-4-Butyrolactone useful for preparing (R)-Carnitine | Sigma-Tau Industrie Farmaceutiche Riunite S.p.A. (IT) | 1999-06-23 | — | — | EP | disclosed |