SCHEMBL195578

SCHEMBL195578

[c]1ccccc1SNc1ccccc1

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 3/20 0.33
ALDH1A1 P00352 2/20 0.33
HSD17B10 Q99714 2/20 0.33
CTSD P07339 1/20 0.33
TSHR P16473 3/20 0.32
TP53 P04637 1/20 0.32
EPHX1 P07099 1/20 0.32
EPHX2 P34913 1/20 0.32
CDK9 P50750 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
CLK4 Q9HAZ1 1/20 0.32
PTGS2 P35354 2/20 0.32
ALOX15 P16050 1/20 0.32
ALOX12 P18054 1/20 0.32
PTGS1 P23219 1/20 0.32
SLC6A2 P23975 1/20 0.32
MAPK1 P28482 1/20 0.32
HTR2B P41595 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
IDO1 P14902 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4763821 0.74
SCHEMBL7933831 0.70 MAPT (0.55) ALDH1A1HSD17B10SMN1; SMN2MAPK1
SCHEMBL8973418 0.69
SCHEMBL4724746 0.69 TDP1 (0.31) TDP1
SCHEMBL4722775 0.69
SCHEMBL2423602 0.69
SCHEMBL819437 0.69 MAPT (0.32) HSD17B10SMN1; SMN2
SCHEMBL440187 0.67
SCHEMBL311562 0.67 HSD17B10 (0.50) TDP1ALDH1A1HSD17B10CTSDTSHR
SCHEMBL237661 0.67 HPGD (0.38) ALDH1A1HSD17B10SMN1; SMN2MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 221 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118324816-A Organometallic compound, light-emitting device, electronic apparatus, and electronic device 三星显示有限公司 2024-07-12 CN claimed
US-11991925-B2 Light-emitting device including condensed cyclic compound and electronic apparatus including the light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2024-05-21 US claimed
CN-117135987-A Organometallic compound, light-emitting device including the same, electronic device, and electronic device 三星显示有限公司 2023-11-28 CN claimed
CN-117062455-A Organic light emitting device and electronic apparatus including the same 三星显示有限公司 2023-11-14 CN claimed
CN-116896914-A Organometallic compound, light-emitting device including the same, electronic device, and electronic device 三星显示有限公司 2023-10-17 CN claimed
CN-116640169-A Organometallic compound, light-emitting device, and electronic device 三星显示有限公司 2023-08-25 CN claimed
CN-116583161-A Light emitting device and electronic apparatus including the same 三星显示有限公司 2023-08-11 CN claimed
CN-116507146-A Heterocyclic compound, light-emitting device including the same, and electronic apparatus 三星显示有限公司 2023-07-28 CN claimed
CN-116437783-A Organometallic compound, light-emitting device, and electronic device 三星显示有限公司 2023-07-14 CN claimed
CN-116265472-A Heterocyclic compound, light-emitting device including the same, and electronic apparatus 三星显示有限公司 2023-06-20 CN claimed
WO-2013119542-A1 COMPOUNDS FOR THE TREATMENT OF HEPATITIS C BRISTOL-MYERS SQUIBB COMPANY (US) 2013-08-15 WO claimed
US-20130203758-A1 Compounds for the Treatment of Hepatitis C BRISTOL-MYERS SQUIBB COMPANY (US) 2013-08-08 US claimed
US-8324217-B2 Cold menthol receptor antagonists JANSSEN PHARMACEUTICA NV (BE) 2012-12-04 US claimed
US-20120136006-A1 COLD MENTHOL RECEPTOR ANTAGONISTS COLBURN RAYMOND W (US) 2012-05-31 US claimed
US-8143259-B2 Cold menthol receptor antagonists JANSSEN PHARMACEUTICA, NV (BE) 2012-03-27 US claimed
JP-2012500267-A 2012-01-05 JP claimed
EP-2331499-A1 COLD MENTHOL RECEPTOR ANTAGONISTS Janssen Pharmaceutica, N.V. (BE) 2011-06-15 EP claimed
WO-2010021878-A1 COLD MENTHOL RECEPTOR ANTAGONISTS JANSSEN PHARMACEUTICA NV (BE) 2010-02-25 WO claimed
US-20100048589-A1 Cold Menthol Receptor Antagonists JANSSEN PHARMACEUTICA NV (BE) 2010-02-25 US claimed
US-20080220286-A1 Electroluminescent compound; high color purity, high fluorescence yield, and high electric luminance yield; easy to synthesize and can easily form films TSINGHUA UNIVERSITY (CN) 2008-09-11 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100048589-A1 Cold Menthol Receptor Antagonists TRPV1, TRPM2, TRPM6 TDP1 4132/4885ALDH1A1 1175/4885HSD17B10 2232/4885
US-20130203758-A1 Compounds for the Treatment of Hepatitis C HAVCR2, SLC10A1, HCCS TDP1 3844/4885ALDH1A1 253/4885HSD17B10 638/4885
US-20120136006-A1 COLD MENTHOL RECEPTOR ANTAGONISTS TRPV1, TRPM2, TRPM6 TDP1 4132/4885ALDH1A1 1175/4885HSD17B10 2232/4885
US-20080220286-A1 Electroluminescent compound; high color purity, high fluorescence yield, and high electric luminance yield; easy to synthesize and can easily form films EED, DDT, RABL6 TDP1 1015/4885ALDH1A1 811/4885HSD17B10 4113/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.