SCHEMBL1956159

SCHEMBL1956159

C=CC[SiH2]Oc1ccccc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.35
LTA4H P09960 1/20 0.35
KCNA3 P22001 1/20 0.34
THRB P10828 1/20 0.34
SMN1; SMN2 Q16637 3/20 0.34
KDM4E B2RXH2 1/20 0.34
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
GLA P06280 1/20 0.33
GAA P10253 1/20 0.33
HTT P42858 1/20 0.33
RAB9A P51151 1/20 0.33
ALDH1A1 P00352 4/20 0.32
TP53 P04637 1/20 0.32
CYP3A4 P08684 1/20 0.32
ALOX15 P16050 1/20 0.32
ALOX12 P18054 1/20 0.32
CA4 P22748 1/20 0.32
AOC2 O75106 2/20 0.32
MAOA P21397 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10607575 0.72 GAA (0.42) TSHRSMN1; SMN2GAAALDH1A1TP53
SCHEMBL461577 0.72 HPGD (0.37) TSHRSMN1; SMN2HTTALDH1A1
SCHEMBL20591619 0.71
SCHEMBL675837 0.71 IDO1 (0.45) TSHRALDH1A1ALOX15
Butadiene SCHEMBL3336285 0.70 LTA4H (0.39) TSHRLTA4HKCNA3THRBSMN1; SMN2
SCHEMBL17259075 0.70 TSHR (0.42) TSHRLTA4HKCNA3THRBSMN1; SMN2
SCHEMBL707316 0.70 CA4 (0.42) TSHRLTA4HKCNA3TP53CA4
SCHEMBL17385717 0.69 L3MBTL1 (0.32)
SCHEMBL15059130 0.69 CYP2C19 (0.38) TSHRSMN1; SMN2KDM4EHTT
SCHEMBL16541144 0.68 CA1 (0.38) SMN1; SMN2RAB9AALDH1A1CYP3A4ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 76 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2554205-B1 MEDICAL DEVICE WITH SLIDEABLE COATING, AND SYRINGE TERUMO CORP (JP) 2020-04-22 EP claimed
CN-1329615-A Hydroboronation process COMMW SCIENT IND RES ORG (AU) 2002-01-02 CN claimed
US-20240016728-A1 CONTINUOUS ADMINISTRATION DEVICE TERUMO KABUSHIKI KAISHA (JP) 2024-01-18 US disclosed
EP-4302800-A1 CONTINUOUS ADMINISTRATION DEVICE TERUMO Kabushiki Kaisha (JP) 2024-01-10 EP disclosed
WO-2023135884-A1 GASKET FOR SYRINGE AND SYRINGE PROVIDED WITH SAME テルモ株式会社 2023-07-20 WO disclosed
CN-110591029-B Preparation method for synthesizing organic silicon modified phenolic resin by ester exchange method 河南工业大学 2021-10-26 CN disclosed
EP-2226088-B1 GASKET FOR SYRINGE AND SYRINGE COMPRISING THE GASKET TERUMO CORP (JP) 2021-08-04 EP disclosed
EP-3064240-B1 NEEDLE-EQUIPPED SYSRINGE, PRE-FILLED SYRINGE, AND MEDICAL LIQUID ADMINISTRATION DEVICE USING SAME TERUMO CORP (JP) 2020-11-25 EP disclosed
EP-2554205-B1 MEDICAL DEVICE WITH SLIDEABLE COATING, AND SYRINGE TERUMO CORP (JP) 2020-04-22 EP disclosed
CN-105682720-B Syringe with needle, prefilled syringe, and medical liquid administration device using the prefilled syringe 泰尔茂株式会社 2020-02-21 CN disclosed
CN-110591029-A Preparation method for synthesizing organic silicon modified phenolic resin by ester exchange method 河南工业大学 2019-12-20 CN disclosed
CN-1333777-A Organoboron derivatives and methods of coupling organic compounds COMMW SCIENT IND RES ORG (AU) 2002-01-30 CN disclosed
CN-1329615-A Hydroboronation process COMMW SCIENT IND RES ORG (AU) 2002-01-02 CN disclosed
CN-1264386-A Alkene borates and process for covalently coupling organic compounds COMMW SCIENT IND RES ORG (AU) 2000-08-23 CN disclosed
CN-1255123-A Method for Covalently Coupling Organic Compounds Using Diboron Derivatives COMMW SCIENT IND RES ORG (AU) 2000-05-31 CN disclosed
US-5367090-A Unsaturated silane monomers ARISTECH CHEMICAL CORPORATION (US) 1994-11-22 US disclosed
US-5332431-A Alkylphenoxy group containing organosilicon compound NIPPON PAINT CO., LTD. (JP) 1994-07-26 US disclosed
US-4645844-A Functionally substituted phenoxyalkyl alkoxysilanes and method for preparing same M&T CHEMICALS INC. (US) 1987-02-24 US disclosed
EP-0024926-B1 METHOD FOR PREPARING ORGANOSILANES M & T CHEMICALS, INC. (US) 1986-12-03 EP disclosed
EP-0024926-A2 Method for preparing organosilanes M & T CHEMICALS, INC. (US) 1981-03-11 EP disclosed