Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 12/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CTSK | P43235 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18089387 | 1.00 | FPR2 (0.45) | FPR2LMNAMAPTALOX12SMN1; SMN2 | |
| SCHEMBL19547869 | 0.90 | FPR2 (0.47) | FPR2LMNAMAPTALOX12SMN1; SMN2 | |
| SCHEMBL18064435 | 0.89 | FPR2 (0.44) | FPR2LMNAMAPTALOX12SMN1; SMN2 | |
| SCHEMBL16748807 | 0.89 | FPR2 (0.44) | FPR2LMNAMAPTALOX12SMN1; SMN2 | |
| SCHEMBL19547845 | 0.88 | FPR2 (0.49) | FPR2SMN1; SMN2NPC1RAB9AMEN1 | |
| SCHEMBL19547876 | 0.86 | FPR2 (0.49) | FPR2SMN1; SMN2NPC1RAB9AMEN1 | |
| SCHEMBL16742481 | 0.85 | FPR2 (0.47) | FPR2NPC1RAB9AMEN1KMT2A | |
| SCHEMBL19563289 | 0.85 | FPR2 (0.47) | FPR2NPC1RAB9AMEN1KMT2A | |
| SCHEMBL16748862 | 0.85 | FPR2 (0.48) | FPR2LMNAMAPTMEN1KMT2A | |
| SCHEMBL16748910 | 0.85 | CDK1 (0.48) | FPR2LMNAMEN1KMT2ACTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3071548-B1 | PHENYLCARBAMATE DERIVATIVES AS FORMYL PEPTIDE RECEPTOR MODULATORS | ALLERGAN INC (US) | 2017-11-08 | — | — | EP | disclosed |