Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19568015 | 0.86 | KMT2A (0.31) | KMT2A | |
| SCHEMBL26275171 | 0.77 | ALDH1A1 (0.50) | KMT2A | |
| SCHEMBL19567369 | 0.74 | JAK2 (0.34) | KMT2A | |
| SCHEMBL24093055 | 0.74 | JAK2 (0.34) | KMT2A | |
| SCHEMBL19567362 | 0.74 | JAK2 (0.34) | KMT2A | |
| SCHEMBL2306469 | 0.74 | — | — | |
| SCHEMBL19567179 | 0.71 | — | — | |
| SCHEMBL19567846 | 0.71 | — | — | |
| SCHEMBL13907209 | 0.71 | JAK2 (0.33) | KMT2A | |
| SCHEMBL2162286 | 0.71 | JAK2 (0.33) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017191098-A1 | PYRAZOLE DERIVATIVES, COMPOSITIONS AND THERAPEUTIC USE THEREOF | F. HOFFMANN-LA ROCHE AG (CH) | 2017-11-09 | — | — | WO | disclosed |