Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | RXRA | P19793 | 1/20 | 0.32 |
| ▸ | RXRB | P28702 | 1/20 | 0.32 |
| ▸ | RXRG | P48443 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.30 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.30 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19564854 | 0.94 | SMN1; SMN2 (0.33) | TSHRPOLBALDH1A1APEX1HTT | |
| SCHEMBL24756135 | 0.89 | GAA (0.40) | TSHRPOLBALDH1A1APEX1HTT | |
| SCHEMBL812232 | 0.87 | ALDH1A1 (0.38) | TSHRPOLBALDH1A1APEX1HTT | |
| SCHEMBL812217 | 0.83 | ALDH1A1 (0.39) | TSHRPOLBALDH1A1MEN1PKM | |
| SCHEMBL822715 | 0.78 | ALDH1A1 (0.36) | TSHRPOLBALDH1A1PKMKMT2A | |
| SCHEMBL16843139 | 0.77 | ALDH1A1 (0.37) | TSHRPOLBALDH1A1MEN1PKM | |
| SCHEMBL19569871 | 0.77 | ALDH1A1 (0.45) | TSHRPOLBALDH1A1MEN1PKM | |
| SCHEMBL811794 | 0.76 | KMT2A (0.43) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL19564847 | 0.76 | THRB (0.39) | TSHRPOLBALDH1A1KMT2AGAA | |
| SCHEMBL19569884 | 0.75 | THRB (0.34) | TSHRPOLBALDH1A1PKMKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170320984-A1 | OPTICAL COMPOSITION, CURED PRODUCT, AND OPTICAL ELEMENT | CANON KABUSHIKI KAISHA (JP) | 2017-11-09 | — | — | US | disclosed |