SCHEMBL195718

SCHEMBL195718

CCCCCCCCCCCCC/C=C/C(O)C(COC1OC(CO)C(OC2OC(CO)C(OC3OC(CO)C(O)C(OC4OC(CO)C(O)C(O)C4O)C3NC(C)=O)C(OC3(C(=O)O)CC(O)C(NC(C)=O)C(C(O)C(O)CO)O3)C2O)C(O)C1O)NC(=O)C(Cl)Cl

nearest known ligand 0.57

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ SIGLEC7 Q9Y286 6/20 0.57
▸ MAG P20916 6/20 0.50
▸ SELL P14151 2/20 0.50
▸ SELP P16109 2/20 0.50
▸ SELE P16581 2/20 0.47
▸ APP P05067 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29380203 0.96 SIGLEC7 (0.57) SIGLEC7MAGSELLSELPSELE
SCHEMBL12313946 0.96 SIGLEC7 (0.57) SIGLEC7MAGSELLSELPSELE
SCHEMBL29699102 0.94 SIGLEC7 (0.57) SIGLEC7MAGSELLSELPSELE
SCHEMBL30649952 0.94 SIGLEC7 (0.56) SIGLEC7MAGSELLSELPSELE
SCHEMBL31126371 0.94 SIGLEC7 (0.56) SIGLEC7MAGSELLSELPSELE
SCHEMBL30651291 0.94 SIGLEC7 (0.56) SIGLEC7MAGSELLSELPSELE
SCHEMBL30650374 0.94 SIGLEC7 (0.56) SIGLEC7MAGSELLSELPSELE
SCHEMBL22969674 0.94 SIGLEC7 (0.56) SIGLEC7MAGSELLSELPSELE
SCHEMBL20971391 0.94 SIGLEC7 (0.56) SIGLEC7MAGSELLSELPSELE
SCHEMBL30649466 0.94 SIGLEC7 (0.56) SIGLEC7MAGSELLSELPSELE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260146254-A1 Enhancing Oligonucleotide Immunomodulatory Activity through Dianophore Long-Lasting Modification: Methods and Applications SEGENA CORPORATION S.A. (UY) 2026-05-28 — — US disclosed
US-12611419-B2 Liposomal composition for use in a method of treating Parkinson's disease INNOMEDICA HOLDING AG (CH) 2026-04-28 — — US disclosed
EP-4622674-A1 ENHANCING OLIGONUCLEOTIDE IMMUNOMODULATORY ACTIVITY THROUGH DIANOPHORE LONG-LASTING MODIFICATION: METHODS AND APPLICATIONS SEGENA CORPORATION S.A. (UY) 2025-10-01 — — EP disclosed
WO-2025064617-A2 LIPOSOMAL FORMULATIONS FOR TREATMENT OF GM1 DEFICIENCIES SENEB BIOSCIENCES, INC. (US) 2025-03-27 — — WO disclosed
EP-4335506-A2 LIPOSOMES COMPRISING SPHINGOMYELIN InnoMedica Holding AG (CH) 2024-03-13 — — EP disclosed
EP-3727328-B1 LIPOSOMES COMPRISING SPHINGOMYELIN INNOMEDICA HOLDING AG (CH) 2024-02-07 — — EP disclosed
US-20230210875-A1 LIPOSOMAL COMPOSITION FOR USE IN A METHOD OF TREATING PARKINSON'S DISEASE INNOMEDICA HOLDING AG (CH) 2023-07-06 — — US disclosed
US-11607385-B2 Liposomes comprising sphingomyelin INNOMEDICA HOLDING AG (CH) 2023-03-21 — — US disclosed
US-20220226357-A1 METHODS FOR TREATING NEURODEGENERATIVE DISORDERS UNIV JEFFERSON (US) 2022-07-21 — — US disclosed
CN-114761021-A Methods for treating neurodegenerative disorders 托马斯杰斐逊大学 2022-07-15 — — CN disclosed
US-20110065696-A1 IMIDAZOYL PYRIDINE COMPOUNDS AND SALTS THEREOF KIMURA TEIJI 2011-03-17 — — US disclosed
US-20110009619-A1 POLYCYCLIC COMPOUND EISAI R&D MANAGEMENT CO., LTD. (JP) 2011-01-13 — — US disclosed
WO-2010098495-A1 IMIDAZOLYLPYRAZINE DERIVATIVES EISAI R&D MANAGEMENT CO., LTD. (JP) 2010-09-02 — — WO disclosed
WO-2010098487-A1 NITROGEN-CONTAINING FUSED HETEROCYCLIC COMPOUNDS AND THEIR USE AS BETA AMYLOID PRODUCTION INHIBITORS EISAI R&D MANAGEMENT CO., LTD. (JP) 2010-09-02 — — WO disclosed
WO-2010098488-A1 ARYL IMIDAZOLE COMPOUNDS AND THEIR USE AS BETA AMYLOID PRODUCTION INHIBITORS EISAI R&D MANAGEMENT CO., LTD. (JP) 2010-09-02 — — WO disclosed
US-20100130537-A1 CINNAMIDE COMPOUNDS FOR DEMENTIA EISAI R&D MANAGEMENT CO., LTD (JP) 2010-05-27 — — US disclosed
EP-2181992-A1 POLYCYCLIC COMPOUND Eisai R&D Management Co., Ltd. (JP) 2010-05-05 — — EP disclosed
EP-2148673-A1 CINNAMIDE COMPOUNDS FOR DEMENTIA Eisai R&D Management Co., Ltd. (JP) 2010-02-03 — — EP disclosed
US-20090062529-A1 MULTI-CYCLIC COMPOUNDS EISAI R&D MANAGEMENT CO., LTD., (JP) 2009-03-05 — — US disclosed
WO-2008139984-A1 CINNAMIDE COMPOUNDS FOR DEMENTIA EISAI R & D MANAGEMENT CO., LTD. (JP) 2008-11-20 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100130537-A1 CINNAMIDE COMPOUNDS FOR DEMENTIA GRIN1, GRIN2A, GRIN3A SIGLEC7 666/4885MAG 774/4885SELL 1093/4885
US-20110009619-A1 POLYCYCLIC COMPOUND APP, BACE1, PSEN1 SIGLEC7 4393/4885MAG 2582/4885SELL 3935/4885
US-12611419-B2 Liposomal composition for use in a method of treating Parkinson's disease SMPD2, SMPD1, SGMS2 SIGLEC7 59/4885MAG 11/4885SELL 148/4885
US-20110065696-A1 IMIDAZOYL PYRIDINE COMPOUNDS AND SALTS THEREOF APP, PSEN1, BACE1 SIGLEC7 4705/4885MAG 2721/4885SELL 4466/4885
US-20230210875-A1 LIPOSOMAL COMPOSITION FOR USE IN A METHOD OF TREATING PARKINSON'S DISEASE GBA1, GALC, SMPD3 SIGLEC7 88/4885MAG 32/4885SELL 1210/4885
US-20090062529-A1 MULTI-CYCLIC COMPOUNDS APP, BACE1, PSEN1 SIGLEC7 4334/4885MAG 1646/4885SELL 4005/4885
US-20260146254-A1 Enhancing Oligonucleotide Immunomodulatory Activity through Dianophore Long-Lasting Modification: Methods and Applications CD44, ADAR, TLR9 SIGLEC7 15/4885MAG 2714/4885SELL 812/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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