Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | ADH1B | P00325 | 1/20 | 0.38 |
| ▸ | ADH1C | P00326 | 1/20 | 0.38 |
| ▸ | ADH1A | P07327 | 1/20 | 0.38 |
| ▸ | ADH4 | P08319 | 1/20 | 0.38 |
| ▸ | ADH7 | P40394 | 1/20 | 0.38 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.36 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27700908 | 0.88 | OPRM1 (0.44) | OPRM1SPHK1LMNADNM1TSHR | |
| SCHEMBL4521414 | 0.88 | OPRM1 (0.44) | OPRM1SPHK1LMNADNM1TSHR | |
| SCHEMBL28495419 | 0.80 | OPRM1 (0.46) | OPRM1SPHK1LMNADNM1TSHR | |
| SCHEMBL21784006 | 0.79 | — | — | |
| SCHEMBL13858988 | 0.79 | OPRM1 (0.55) | OPRM1SPHK1LMNADNM1TSHR | |
| SCHEMBL325629 | 0.79 | OPRM1 (0.55) | OPRM1SPHK1LMNADNM1TSHR | |
| SCHEMBL11486416 | 0.79 | OPRM1 (0.55) | OPRM1SPHK1LMNADNM1TSHR | |
| SCHEMBL10657571 | 0.79 | OPRM1 (0.55) | OPRM1SPHK1LMNADNM1TSHR | |
| SCHEMBL11480610 | 0.79 | OPRM1 (0.55) | OPRM1SPHK1LMNADNM1TSHR | |
| SCHEMBL31169240 | 0.79 | OPRM1 (0.55) | OPRM1SPHK1LMNADNM1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017191297-A1 | ADENINE DERIVATIVES AS PROTEIN KINASE INHIBITORS | BCI PHARMA (FR) | 2017-11-09 | — | — | WO | disclosed |