⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19575554 | 0.79 | OPRM1 (0.42) | — | |
| SCHEMBL7875883 | 0.72 | — | — | |
| SCHEMBL12127156 | 0.70 | — | — | |
| SCHEMBL15711219 | 0.70 | — | — | |
| SCHEMBL3929380 | 0.69 | — | — | |
| SCHEMBL7736871 | 0.69 | — | — | |
| SCHEMBL20842562 | 0.69 | ALDH1A1 (0.30) | — | |
| SCHEMBL12948269 | 0.69 | LMNA (0.38) | — | |
| SCHEMBL28999210 | 0.69 | — | — | |
| SCHEMBL28999327 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020047061-A1 | IMPROVED PROCESS OF PREPARING MRNA-LOADED LIPID NANOPARTICLES | TRANSLATE BIO, INC. (US) | 2020-03-05 | — | — | WO | disclosed |