Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24576787 | 0.85 | TAAR1 (0.47) | TAAR1SMN1; SMN2SLC18A3MEN1KMT2A | |
| SCHEMBL24576451 | 0.85 | TAAR1 (0.47) | TAAR1SMN1; SMN2SLC18A3MEN1KMT2A | |
| SCHEMBL22415955 | 0.82 | OPRK1 (0.45) | SMN1; SMN2MEN1KMT2ARAB9AALDH1A1 | |
| SCHEMBL19576648 | 0.79 | TAAR1 (0.44) | TAAR1SMN1; SMN2MEN1KMT2ACTSK | |
| SCHEMBL7452644 | 0.77 | TAAR1 (0.53) | TAAR1SMN1; SMN2MEN1KMT2ACTSK | |
| SCHEMBL19576639 | 0.77 | PEPD (0.34) | TAAR1 | |
| SCHEMBL7452648 | 0.77 | TAAR1 (0.53) | TAAR1SMN1; SMN2MEN1KMT2ACTSK | |
| SCHEMBL7230439 | 0.77 | TAAR1 (0.53) | TAAR1SMN1; SMN2MEN1KMT2ACTSK | |
| SCHEMBL19576744 | 0.76 | TAS2R14 (0.38) | SMN1; SMN2KMT2ASLC6A4 | |
| SCHEMBL6742208 | 0.75 | TAAR1 (0.40) | TAAR1CTSKRAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3452485-B1 | ARGINASE INHIBITORS AND THEIR THERAPEUTIC APPLICATIONS | ONCOARENDI THERAPEUTICS SA (PL) | 2020-09-09 | — | — | EP | disclosed |
| WO-2017191130-A2 | ARGINASE INHIBITORS AND THEIR THERAPEUTIC APPLICATIONS | ONCOARENDI THERAPEUTICS SA (PL) | 2017-11-09 | — | — | WO | disclosed |