Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC34A2 | O95436 | 7/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | CARM1 | Q86X55 | 2/20 | 0.34 |
| ▸ | EGFR | P00533 | 2/20 | 0.34 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.34 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.34 |
| ▸ | RAF1 | P04049 | 2/20 | 0.33 |
| ▸ | BRAF | P15056 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19580041 | 0.91 | SLC34A2 (0.54) | SLC34A2MAPTRAF1BRAFSMN1; SMN2 | |
| SCHEMBL19579973 | 0.89 | SLC34A2 (0.53) | SLC34A2MAPTLMNASMN1; SMN2 | |
| SCHEMBL19596292 | 0.87 | MAPT (0.41) | MAPTCARM1PRMT6PRMT8RAF1 | |
| SCHEMBL19595685 | 0.85 | SLC34A2 (0.46) | SLC34A2MAPTSMN1; SMN2 | |
| SCHEMBL19579983 | 0.85 | SLC34A2 (0.46) | SLC34A2MAPTRAF1BRAFLMNA | |
| SCHEMBL19579946 | 0.85 | SLC34A2 (0.51) | SLC34A2MAPTLMNA | |
| SCHEMBL19579965 | 0.84 | SLC34A2 (0.47) | SLC34A2EGFRLMNA | |
| SCHEMBL39824 | 0.83 | SLC34A2 (0.44) | SLC34A2MAPTLMNASMN1; SMN2 | |
| SCHEMBL46435 | 0.83 | SLC34A2 (0.47) | SLC34A2MAPTLMNA | |
| SCHEMBL19580004 | 0.83 | SLC34A2 (0.52) | SLC34A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2590656-B1 | COMPOUNDS AND METHODS FOR INHIBITING PHOSPHATE TRANSPORT | ARDELYX INC (US) | 2017-11-15 | — | — | EP | claimed |