Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC34A2 | O95436 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 10/20 | 0.43 |
| ▸ | NPC1 | O15118 | 9/20 | 0.43 |
| ▸ | RAB9A | P51151 | 8/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.43 |
| ▸ | TP53 | P04637 | 3/20 | 0.43 |
| ▸ | PKM | P14618 | 3/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15444403 | 0.93 | SLC34A2 (0.45) | SLC34A2MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL19595685 | 0.92 | SLC34A2 (0.46) | SLC34A2MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL39824 | 0.92 | SLC34A2 (0.44) | SLC34A2MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6000093 | 0.92 | SLC34A2 (0.54) | SLC34A2MAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL19579995 | 0.90 | SLC34A2 (0.43) | SLC34A2MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL46435 | 0.90 | SLC34A2 (0.47) | SLC34A2MAPTTP53LMNAKDM4E | |
| SCHEMBL19579947 | 0.90 | SLC34A2 (0.53) | SLC34A2 | |
| SCHEMBL19580004 | 0.90 | SLC34A2 (0.52) | SLC34A2PARP1 | |
| SCHEMBL19579978 | 0.89 | SLC34A2 (0.51) | SLC34A2 | |
| SCHEMBL19579942 | 0.89 | SLC34A2 (0.42) | SLC34A2MAPTNPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2590656-B1 | COMPOUNDS AND METHODS FOR INHIBITING PHOSPHATE TRANSPORT | ARDELYX INC (US) | 2017-11-15 | — | — | EP | claimed |