Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1870366 | 0.82 | SCN9A (0.32) | SCN9A | |
| SCHEMBL1865903 | 0.76 | — | — | |
| SCHEMBL1700364 | 0.71 | SCN9A (0.33) | SCN9A | |
| SCHEMBL1959260 | 0.70 | IRAK4 (0.38) | SCN5ASCN9A | |
| SCHEMBL1863585 | 0.70 | SOS1 (0.35) | SCN5ASCN9A | |
| SCHEMBL1700611 | 0.65 | SCN9A (0.43) | SCN5ASCN9A | |
| Trifluoroacetic Acid SCHEMBL1700071 | 0.65 | IRAK4 (0.37) | SCN5ASCN9A | |
| SCHEMBL29629045 | 0.64 | IKBKB (0.50) | SCN9A | |
| SCHEMBL1700623 | 0.64 | SCN9A (0.39) | SCN5ASCN9A | |
| SCHEMBL1700491 | 0.64 | CA2 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2507229-A1 | SULFONAMIDE DERIVATIVES AS BCL-2-SELECTIVE APOPTOSIS-INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE DISEASES | Abbott Laboratories (US) | 2012-10-10 | — | — | EP | disclosed |
| WO-2011068561-A1 | SULFONAMIDE DERIVATIVES AS BCL-2-SELECTIVE APOPTOSIS-INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE DISEASES | ABBOTT LABORATORIES (US) | 2011-06-09 | — | — | WO | disclosed |