SCHEMBL19583100

SCHEMBL19583100

OC[C@H]1O[C@@H](n2cnc3c(NCc4ccc(O)o4)ncnc32)[C@@H](O)[C@@H]1O

nearest known ligand 0.73

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ SLC29A1 Q99808 4/20 0.73
▸ ADORA3 P0DMS8 4/20 0.73
▸ TP53 P04637 3/20 0.73
▸ PAX8 Q06710 3/20 0.73
▸ SMN1; SMN2 Q16637 1/20 0.73
▸ MITF O75030 1/20 0.73
▸ LMNA P02545 1/20 0.73
▸ TDP1 Q9NUW8 1/20 0.71
▸ PRKAG1 P54619 1/20 0.69
▸ PRKAA1 Q13131 1/20 0.69
▸ PRKAB1 Q9Y478 1/20 0.69
▸ ADORA2A P29274 1/20 0.67
▸ ADORA1 P30542 1/20 0.67
▸ TSHR P16473 1/20 0.67
▸ NFKB1 P19838 1/20 0.67
▸ STAT6 P42226 1/20 0.67
▸ GMNN O75496 1/20 0.67
▸ BLM P54132 1/20 0.67
▸ PMP22 Q01453 1/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17825928 1.00 SLC29A1 (0.73) SLC29A1ADORA3TP53PAX8SMN1; SMN2
SCHEMBL19583070 0.90 SLC29A1 (0.72) SLC29A1ADORA3TP53PAX8SMN1; SMN2
SCHEMBL19583011 0.90 SLC29A1 (0.72) SLC29A1ADORA3TP53PAX8SMN1; SMN2
SCHEMBL17825992 0.90 ADORA3 (0.72) SLC29A1ADORA3TP53PAX8SMN1; SMN2
SCHEMBL17826002 0.90 SLC29A1 (0.72) SLC29A1ADORA3TP53PAX8SMN1; SMN2
SCHEMBL17825994 0.90 SLC29A1 (0.72) SLC29A1ADORA3TP53PAX8SMN1; SMN2
SCHEMBL14713281 0.90 ADORA3 (0.72) SLC29A1ADORA3TP53PAX8SMN1; SMN2
SCHEMBL20626318 0.90 ADORA3 (0.72) SLC29A1ADORA3TP53PAX8SMN1; SMN2
SCHEMBL20626317 0.90 ADORA3 (0.72) SLC29A1ADORA3TP53PAX8SMN1; SMN2
SCHEMBL19583113 0.90 ADORA3 (0.72) SLC29A1ADORA3TP53PAX8SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3229771-B1 6-ARYL-9-GLYCOSYLPURINES AND USE THEREOF UNIV PALACKEHO (CZ) 2024-04-03 — — EP claimed
EP-3229772-B1 6-ARYL-9-GLYCOSYLPURINES AND USE THEREOF UNIV PALACKEHO (CZ) 2020-04-29 — — EP claimed
US-10550144-B2 6-aryl-9-glycosylpurines and use thereof UNIVERZITA PALACKEHO V OLOMOUCI (CZ) 2020-02-04 — — US claimed
US-10100077-B2 6-aryl-9-glycosylpurines and use thereof UNIVERZITA PALACKEHO V OLOMOUCI (CZ) 2018-10-16 — — US claimed
US-20170334943-A1 6-ARYL-9-GLYCOSYLPURINES AND USE THEREOF UNIVERZITA PALACKEHO V OLOMOUCI (CZ) 2017-11-23 — — US claimed
US-20170326168-A1 6-ARYL-9-GLYCOSYLPURINES AND USE THEREOF UNIVERZITA PALACKEHO V OLOMOUCI (CZ) 2017-11-16 — — US claimed
EP-3229771-B1 6-ARYL-9-GLYCOSYLPURINES AND USE THEREOF UNIV PALACKEHO (CZ) 2024-04-03 — — EP disclosed
EP-3229772-B1 6-ARYL-9-GLYCOSYLPURINES AND USE THEREOF UNIV PALACKEHO (CZ) 2020-04-29 — — EP disclosed
US-10550144-B2 6-aryl-9-glycosylpurines and use thereof UNIVERZITA PALACKEHO V OLOMOUCI (CZ) 2020-02-04 — — US disclosed
US-10100077-B2 6-aryl-9-glycosylpurines and use thereof UNIVERZITA PALACKEHO V OLOMOUCI (CZ) 2018-10-16 — — US disclosed
US-20170334943-A1 6-ARYL-9-GLYCOSYLPURINES AND USE THEREOF UNIVERZITA PALACKEHO V OLOMOUCI (CZ) 2017-11-23 — — US disclosed
US-20170326168-A1 6-ARYL-9-GLYCOSYLPURINES AND USE THEREOF UNIVERZITA PALACKEHO V OLOMOUCI (CZ) 2017-11-16 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170326168-A1 6-ARYL-9-GLYCOSYLPURINES AND USE THEREOF GART, DAO, GLA SLC29A1 125/4885ADORA3 553/4885TP53 3135/4885
US-10550144-B2 6-aryl-9-glycosylpurines and use thereof GART, DAO, GLA SLC29A1 125/4885ADORA3 553/4885TP53 3135/4885
US-20170334943-A1 6-ARYL-9-GLYCOSYLPURINES AND USE THEREOF UNG, FUT6, GART SLC29A1 59/4885ADORA3 387/4885TP53 2090/4885
US-10100077-B2 6-aryl-9-glycosylpurines and use thereof UNG, FUT6, GART SLC29A1 59/4885ADORA3 387/4885TP53 2090/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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