SCHEMBL19583199

SCHEMBL19583199

C=C(C)C(=O)OC(OCCCC)OCCCC

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.50
ALDH1A1 P00352 2/20 0.41
THRB P10828 2/20 0.39
HPGD P15428 2/20 0.36
POLB P06746 1/20 0.36
APEX1 P27695 1/20 0.36
HTT P42858 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
ATM Q13315 1/20 0.34
THRA P10827 1/20 0.33
CES2 O00748 1/20 0.32
LMNA P02545 3/20 0.32
ESR1 P03372 1/20 0.32
CYP1A2 P05177 1/20 0.32
CYP2D6 P10635 1/20 0.32
MAPK1 P28482 1/20 0.32
CYP2C19 P33261 1/20 0.32
NR1H2 P55055 1/20 0.32
RNASEL Q05823 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL196351 0.84 TSHR (0.49) TSHRALDH1A1THRBHPGDPOLB
SCHEMBL27497028 0.82 TSHR (0.36) TSHRALDH1A1HPGDATMCES2
SCHEMBL36758 0.82 TSHR (0.47) TSHRALDH1A1THRBHPGDPOLB
SCHEMBL15049993 0.81 TSHR (0.39) TSHRALDH1A1THRB
SCHEMBL2948546 0.81 TSHR (0.46) TSHRALDH1A1THRBHPGDPOLB
SCHEMBL7634474 0.80 THRB (0.44) TSHRALDH1A1THRBLMNA
SCHEMBL6928059 0.80 TSHR (0.40) TSHRALDH1A1THRB
SCHEMBL5820402 0.80 TSHR (0.45) TSHRALDH1A1THRBHPGDPOLB
SCHEMBL7628396 0.80 TSHR (0.45) TSHRALDH1A1THRBHPGDPOLB
SCHEMBL15306388 0.80 TSHR (0.45) TSHRALDH1A1THRBHPGDPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3555677-B1 HIGH REFRACTIVE INDEX HYDROPHILIC MATERIALS BENZ RES AND DEVELOPMENT CORPORATION (US) 2022-04-20 EP disclosed
CN-109475660-B Hydrophobic intraocular lenses 宾视研发公司 2022-03-22 CN disclosed
EP-3458118-B1 HYDROPHOBIC INTRAOCULAR LENS BENZ RES AND DEVELOPMENT CORPORATION (US) 2021-10-27 EP disclosed
US-10899862-B2 Hydrophobic intraocular lens BENZ RESEARCH AND DEVELOPMENT CORP. (US) 2021-01-26 US disclosed
US-10894111-B2 High refractive index hydrophilic materials BENZ RESEARCH AND DEVELOPMENT CORP. (US) 2021-01-19 US disclosed
EP-3555677-A1 HIGH REFRACTIVE INDEX HYDROPHILIC MATERIALS Benz Research And Development Corporation (US) 2019-10-23 EP disclosed
EP-3458118-A1 HYDROPHOBIC INTRAOCULAR LENS Benz Research And Development Corporation (US) 2019-03-27 EP disclosed
US-10196470-B2 Hydrophobic intraocular lens BENZ RESEARCH AND DEVELOPMENT CORP. (US) 2019-02-05 US disclosed
US-20180334520-A1 HYDROPHOBIC INTRAOCULAR LENS BENZ RESEARCH AND DEVELOPMENT CORP. (US) 2018-11-22 US disclosed
WO-2018112180-A1 HIGH REFRACTIVE INDEX HYDROPHILIC MATERIALS BENZ RESEARCH AND DEVELOPMENT CORP. (US) 2018-06-21 WO disclosed
CN-108137722-A RAFT polymer without thio-carbonyl sulfide and preparation method thereof 汉高知识产权控股有限责任公司 2018-06-08 CN disclosed
CN-107922344-A general RAFT agent 联邦科学与工业研究组织 2018-04-17 CN disclosed
WO-2017200934-A1 HYDROPHOBIC INTRAOCULAR LENS BENZ RESEARCH AND DEVELOPMENT CORP. (US) 2017-11-23 WO disclosed
US-20170327615-A1 HYDROPHOBIC INTRAOCULAR LENS BENZ RESEARCH AND DEVELOPMENT CORP. (US) 2017-11-16 US disclosed
CN-102099010-B The compositions that can give 悉尼大学 2016-09-14 CN disclosed
CN-104640972-A Release medium UNIV QUEENSLAND 2015-05-20 CN disclosed
CN-102883813-A High capacity ion chromatography stationary phase and method of formation DIONEX CORP 2013-01-16 CN disclosed
CN-102099010-A Administrable compositions UNIV SYDNEY 2011-06-15 CN disclosed
CN-102076328-A Micelles for intracellular delivery of therapeutic agents UNIV WASHINGTON 2011-05-25 CN disclosed
CN-102065902-A Polymeric carrier UNIV WASHINGTON 2011-05-18 CN disclosed