SCHEMBL6928059

SCHEMBL6928059

C=C(C)C(=O)OC(CC)[SiH2]OC(OCCCC)OCCCC

nearest known ligand 0.40

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.40
ALDH1A1 P00352 1/20 0.32
THRB P10828 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1017353 0.82 TSHR (0.44) TSHRALDH1A1THRB
SCHEMBL19583199 0.80 TSHR (0.50) TSHRALDH1A1THRB
SCHEMBL140537 0.80 TSHR (0.41) TSHRALDH1A1THRB
SCHEMBL3278987 0.77 TSHR (0.39) TSHRALDH1A1THRB
SCHEMBL5308928 0.77 TSHR (0.35) TSHRALDH1A1THRB
SCHEMBL2491513 0.75 TSHR (0.37) TSHRALDH1A1THRB
SCHEMBL22371482 0.74 TSHR (0.41) TSHRALDH1A1THRB
SCHEMBL36758 0.74 TSHR (0.47) TSHRALDH1A1THRB
SCHEMBL1014718 0.74 ALDH1A1 (0.40) TSHRALDH1A1THRB
SCHEMBL29076717 0.74 TSHR (0.36) TSHRALDH1A1THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6518364-B2 Subjecting mixture of monomer(s), water, surfactant, free radical source and a control agent to polymerization SYMYX TECHNOLOGIES, INC. 2003-02-11 US disclosed