SCHEMBL19583243

SCHEMBL19583243

C=C(C)C(=O)NCC(O)COc1ccc(Br)cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.57
ALDH1A1 P00352 4/20 0.56
MEN1 O00255 3/20 0.56
KMT2A Q03164 3/20 0.56
KDM4E B2RXH2 2/20 0.56
TDP1 Q9NUW8 2/20 0.56
SMN1; SMN2 Q16637 1/20 0.56
MAPK1 P28482 2/20 0.53
GAA P10253 1/20 0.53
HPGD P15428 1/20 0.53
HTT P42858 1/20 0.53
LMNA P02545 1/20 0.47
POLB P06746 1/20 0.47
NPSR1 Q6W5P4 1/20 0.47
CYP1A2 P05177 2/20 0.46
CYP2C19 P33261 2/20 0.46
ADRB2 P07550 1/20 0.46
ADRB1 P08588 1/20 0.46
ADRB3 P13945 1/20 0.46
OPRK1 P41145 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14783136 0.86 CYP2D6 (0.56) MAPTALDH1A1MEN1KMT2ASMN1; SMN2
SCHEMBL19583197 0.80 MAPT (0.55) MAPTALDH1A1MEN1KMT2AKDM4E
SCHEMBL19583229 0.78 MAPT (0.53) MAPTALDH1A1MEN1KMT2AKDM4E
SCHEMBL6255835 0.74 ABCB1 (0.56) MAPTALDH1A1MEN1KMT2AKDM4E
SCHEMBL12835269 0.73 CYP1A2 (0.64) MAPTALDH1A1MEN1KMT2ATDP1
SCHEMBL6255838 0.72 MAPT (0.59) MAPTALDH1A1MEN1KMT2AKDM4E
SCHEMBL3738357 0.72 TGFBR1 (0.41) ALDH1A1KDM4ETDP1LMNAPOLB
SCHEMBL24933781 0.71 MAPT (0.51) MAPTALDH1A1MEN1KMT2AKDM4E
SCHEMBL30240819 0.71 MAPT (0.51) MAPTALDH1A1MEN1KMT2AKDM4E
SCHEMBL1496758 0.71 MAPK1 (0.62) MAPTALDH1A1MEN1KMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12226545-B2 Micro injectable, low chromatic aberration intraocular lens materials BENZ RESEARCH AND DEVELOPMENT CORP (US) 2025-02-18 US disclosed
CN-110462448-B Hydrophilic material with high refractive index 宾视研发公司 2023-08-01 CN disclosed
CN-110891618-B Microinjectable, low color aberration intraocular lens materials 宾视研发公司 2023-01-03 CN disclosed
US-20220249737-A1 MICRO INJECTABLE, LOW CHROMATIC ABERRATION INTRAOCULAR LENS MATERIALS BENZ RESEARCH AND DEVELOPMENT CORP. (US) 2022-08-11 US disclosed
EP-3555677-B1 HIGH REFRACTIVE INDEX HYDROPHILIC MATERIALS BENZ RES AND DEVELOPMENT CORPORATION (US) 2022-04-20 EP disclosed
CN-109475660-B Hydrophobic intraocular lenses 宾视研发公司 2022-03-22 CN disclosed
EP-3458118-B1 HYDROPHOBIC INTRAOCULAR LENS BENZ RES AND DEVELOPMENT CORPORATION (US) 2021-10-27 EP disclosed
US-10899862-B2 Hydrophobic intraocular lens BENZ RESEARCH AND DEVELOPMENT CORP. (US) 2021-01-26 US disclosed
US-10894111-B2 High refractive index hydrophilic materials BENZ RESEARCH AND DEVELOPMENT CORP. (US) 2021-01-19 US disclosed
US-20200330643-A1 MICRO INJECTABLE, LOW CHROMATIC ABERRATION INTRAOCULAR LENS MATERIALS BENZ RESEARCH AND DEVELOPMENT CORP. (US) 2020-10-22 US disclosed
EP-3624861-A1 MICRO INJECTABLE, LOW CHROMATIC ABERRATION INTRAOCULAR LENS MATERIALS Benz Research And Development Corporation (US) 2020-03-25 EP disclosed
CN-110891618-A Microinjectable, low color aberration intraocular lens materials 宾视研发公司 2020-03-17 CN disclosed
EP-3555677-A1 HIGH REFRACTIVE INDEX HYDROPHILIC MATERIALS Benz Research And Development Corporation (US) 2019-10-23 EP disclosed
US-10196470-B2 Hydrophobic intraocular lens BENZ RESEARCH AND DEVELOPMENT CORP. (US) 2019-02-05 US disclosed
US-20180334520-A1 HYDROPHOBIC INTRAOCULAR LENS BENZ RESEARCH AND DEVELOPMENT CORP. (US) 2018-11-22 US disclosed
WO-2018213240-A1 MICRO INJECTABLE, LOW CHROMATIC ABERRATION INTRAOCULAR LENS MATERIALS BENZ RESEARCH AND DEVELOPMENT CORP. (US) 2018-11-22 WO disclosed
WO-2018112180-A1 HIGH REFRACTIVE INDEX HYDROPHILIC MATERIALS BENZ RESEARCH AND DEVELOPMENT CORP. (US) 2018-06-21 WO disclosed
US-20180169296-A1 HIGH REFRACTIVE INDEX HYDROPHILIC MATERIALS BENZ RESEARCH AND DEVELOPMENT CORP. (US) 2018-06-21 US disclosed
US-20170327615-A1 HYDROPHOBIC INTRAOCULAR LENS BENZ RESEARCH AND DEVELOPMENT CORP. (US) 2017-11-16 US disclosed