SCHEMBL14783136

SCHEMBL14783136

C=C(C)C(=O)NCC(O)COc1ccccc1

nearest known ligand 0.56

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 2/20 0.56
ADRB2 P07550 2/20 0.56
ADRB1 P08588 2/20 0.56
ADRB3 P13945 2/20 0.56
MAPT P10636 3/20 0.55
CYP1A2 P05177 2/20 0.53
CYP3A4 P08684 1/20 0.53
CYP2C9 P11712 1/20 0.53
CYP2C19 P33261 1/20 0.53
MEN1 O00255 2/20 0.51
ALDH1A1 P00352 2/20 0.51
KMT2A Q03164 2/20 0.51
ATM Q13315 1/20 0.50
HTT P42858 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
MTNR1A P48039 2/20 0.49
MTNR1B P49286 2/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19583243 0.86 MAPT (0.57) CYP2D6ADRB2ADRB1ADRB3MAPT
SCHEMBL6630532 0.85 MAPT (0.64) CYP2D6ADRB2ADRB1ADRB3MAPT
SCHEMBL6630527 0.82 CYP2D6 (0.58) CYP2D6ADRB2ADRB1ADRB3MAPT
SCHEMBL6553912 0.82 CYP2D6 (0.61) CYP2D6ADRB2ADRB1ADRB3MAPT
Methacrylic Acid SCHEMBL28914843 0.82 LMNA (0.57) CYP2D6ADRB2ADRB1ADRB3MAPT
SCHEMBL1027989 0.79 MTNR1A (0.51) MAPTALDH1A1KMT2ASMN1; SMN2MTNR1A
SCHEMBL14783698 0.78 CYP2D6 (0.54) CYP2D6ADRB2ADRB1ADRB3MAPT
SCHEMBL11040659 0.78 LMNA (0.50) CYP2D6ADRB2ADRB1ADRB3MAPT
SCHEMBL7096059 0.78 CYP2D6 (0.56) CYP2D6ADRB2ADRB1ADRB3MAPT
SCHEMBL219561 0.77 MAPT (0.51) CYP2D6ADRB2ADRB1ADRB3MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12226545-B2 Micro injectable, low chromatic aberration intraocular lens materials BENZ RESEARCH AND DEVELOPMENT CORP (US) 2025-02-18 US disclosed
US-20250032398-A1 HIGH MOLECULAR WEIGHT BLOCK COPOLYMERS COMPRISING REPEATING UNITS DERIVED FROM MONOMERS COMPRISING LACTAM AND ACRYLOYL MOIETIES AND HYDROPHILIC MONOMERS, COMPOSITIONS, AND APPLICATIONS THEREOF ISP INVESTMENTS LLC (US) 2025-01-30 US disclosed
CN-110462448-B Hydrophilic material with high refractive index 宾视研发公司 2023-08-01 CN disclosed
CN-110891618-B Microinjectable, low color aberration intraocular lens materials 宾视研发公司 2023-01-03 CN disclosed
US-20220389245-A1 METAL OXIDE NANOPARTICLES BASF SE (DE) 2022-12-08 US disclosed
US-20220249737-A1 MICRO INJECTABLE, LOW CHROMATIC ABERRATION INTRAOCULAR LENS MATERIALS BENZ RESEARCH AND DEVELOPMENT CORP. (US) 2022-08-11 US disclosed
EP-3555677-B1 HIGH REFRACTIVE INDEX HYDROPHILIC MATERIALS BENZ RES AND DEVELOPMENT CORPORATION (US) 2022-04-20 EP disclosed
CN-109475660-B Hydrophobic intraocular lenses 宾视研发公司 2022-03-22 CN disclosed
US-11274219-B2 Surface functionalized titanium dioxide nanoparticles BASF SE (DE) 2022-03-15 US disclosed
EP-3458118-B1 HYDROPHOBIC INTRAOCULAR LENS BENZ RES AND DEVELOPMENT CORPORATION (US) 2021-10-27 EP disclosed
WO-2018132548-A1 CROSS-LINKED BLOCK COPOLYMERS COMPRISING REPEATING UNITS DERIVED FROM MONOMERS COMPRISING LACTAM AND ACRYLOYL MOIETIES, COMPOSITIONS, AND APPLICATIONS THEREOF ISP INVESTMENTS LLC (US) 2018-07-19 WO disclosed
US-20180169296-A1 HIGH REFRACTIVE INDEX HYDROPHILIC MATERIALS BENZ RESEARCH AND DEVELOPMENT CORP. (US) 2018-06-21 US disclosed
WO-2018112180-A1 HIGH REFRACTIVE INDEX HYDROPHILIC MATERIALS BENZ RESEARCH AND DEVELOPMENT CORP. (US) 2018-06-21 WO disclosed
WO-2017200934-A1 HYDROPHOBIC INTRAOCULAR LENS BENZ RESEARCH AND DEVELOPMENT CORP. (US) 2017-11-23 WO disclosed
US-20170327615-A1 HYDROPHOBIC INTRAOCULAR LENS BENZ RESEARCH AND DEVELOPMENT CORP. (US) 2017-11-16 US disclosed
US-20170027685-A1 HYDROPHOBIC INTRAOCULAR LENS BENZ RESEARCH AND DEVELOPMENT CORPORATION (US) 2017-02-02 US disclosed
US-9381080-B2 Hydrophobic intraocular lens BENZ RESEARCH AND DEVELOPMENT CORP. (US) 2016-07-05 US disclosed
EP-2756014-A1 HYDROPHOBIC INTRAOCULAR LENS Benz Research And Development Corporation (US) 2014-07-23 EP disclosed
US-20130253159-A1 HYDROPHOBIC INTRAOCULAR LENS BENZ RESEARCH AND DEVELOPMENT CORP. 2013-09-26 US disclosed
WO-2013040434-A1 HYDROPHOBIC INTRAOCULAR LENS BENZ RESEARCH AND DEVELOPMENT CORP. (US) 2013-03-21 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250032398-A1 HIGH MOLECULAR WEIGHT BLOCK COPOLYMERS COMPRISING REPEATING UNITS DERIVED FROM MONOMERS COMPRISING LACTAM AND ACRYLOYL MOIETIES AND HYDROPHILIC MONOMERS, COMPOSITIONS, AND APPLICATIONS THEREOF PCNA, ADSL, APH1B CYP2D6 3796/4885ADRB2 3925/4885ADRB1 3207/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.