Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OGA | O60502 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 5/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23127812 | 0.85 | OGA (0.39) | OGACA12CA1CA2CA9 | |
| SCHEMBL23813680 | 0.85 | OGA (0.39) | OGACA12CA1CA2CA9 | |
| SCHEMBL21339449 | 0.84 | OGA (0.38) | OGATSHRALOX15 | |
| SCHEMBL6200735 | 0.78 | OGA (0.41) | OGACA12CA1CA2CA9 | |
| SCHEMBL25758783 | 0.74 | TSHR (0.38) | OGACA12CA1CA2CA9 | |
| SCHEMBL25070626 | 0.73 | OGA (0.40) | OGACA12CA1CA2CA9 | |
| SCHEMBL8431814 | 0.72 | CA2 (0.48) | OGACA12CA1CA2CA9 | |
| SCHEMBL20068297 | 0.72 | CA2 (0.48) | OGACA12CA1CA2CA9 | |
| SCHEMBL21339450 | 0.72 | OGA (0.36) | OGACA12CA1CA2CA9 | |
| SCHEMBL13663076 | 0.72 | CA2 (0.48) | OGACA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9816069-B2 | Methods and compositions for making antibodies and antibody derivatives with reduced core fucosylation | SEATTLE GENETICS, INC. (US) | 2017-11-14 | — | — | US | disclosed |