SCHEMBL21339449

SCHEMBL21339449

C=C(C)C1C[C@@H](O)[C@H](OC(C)=O)C(OC(C)=O)O1

nearest known ligand 0.38

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ OGA O60502 1/20 0.38
▸ TSHR P16473 2/20 0.33
▸ ALOX15 P16050 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19588730 0.84 OGA (0.38) OGATSHRALOX15
SCHEMBL15369268 0.70 OGA (0.43) OGA
SCHEMBL20229509 0.69 OGA (0.45) OGATSHR
SCHEMBL1130665 0.69 OGA (0.45) OGATSHR
SCHEMBL23813680 0.69 OGA (0.39) OGATSHR
SCHEMBL23127812 0.69 OGA (0.39) OGATSHR
SCHEMBL10819153 0.67 OGA (0.43) OGATSHR
SCHEMBL25503323 0.66 OGA (0.53) OGATSHR
SCHEMBL13341455 0.65 OGA (0.44) OGATSHR
SCHEMBL18082004 0.65 OGA (0.44) OGATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11319526-B2 Methods and compositions for making antibodies and antibody derivatives with reduced core fucosylation SEAGEN INC. (US) 2022-05-03 — — US disclosed
US-20190276796-A1 METHODS AND COMPOSITIONS FOR MAKING ANTIBODIES AND ANTIBODY DERIVATIVES WITH REDUCED CORE FUCOSYLATION SEAGEN INC. 2019-09-12 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190276796-A1 METHODS AND COMPOSITIONS FOR MAKING ANTIBODIES AND ANTIBODY DERIVATIVES WITH REDUCED CORE FUCOSYLATION FUT5, FUCA2, FCGR3B OGA 85/4885TSHR 1665/4885ALOX15 3275/4885
US-11319526-B2 Methods and compositions for making antibodies and antibody derivatives with reduced core fucosylation FUT5, FUCA2, FCGR3B OGA 85/4885TSHR 1665/4885ALOX15 3275/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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