SCHEMBL19590602

SCHEMBL19590602

CC1Cc2c(c3ccccc3n2CCF)C(C)C1

nearest known ligand 0.45

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TSPO P30536 1/20 0.44
SIGMAR1 Q99720 3/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19590537 0.89 TSPO (0.40) TSPO
SCHEMBL902807 0.82 TSPO (0.52) TSPO
SCHEMBL21696319 0.78 TSPO (0.59) TSPO
SCHEMBL417922 0.77 TSPO (0.70) TSPO
SCHEMBL15118336 0.77 TSPO (0.70) TSPO
SCHEMBL413917 0.69 TSPO (0.62) TSPO
SCHEMBL22498229 0.66 CYP1A2 (0.64)
SCHEMBL417887 0.65 TSPO (0.69) TSPO
SCHEMBL28318300 0.63 TSPO (0.47) TSPO
SCHEMBL417897 0.63 TSPO (0.71) TSPO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9815785-B2 Enantiomeric separation and purification of 2,3,4,9-tetrahydro-1H-carbazole-4-carboxylic acid amide derivatives GE HEALTHCARE LIMITED (GB) 2017-11-14 US disclosed