Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSPO | P30536 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL417922 | 0.85 | TSPO (0.70) | TSPO | |
| SCHEMBL15118336 | 0.85 | TSPO (0.70) | TSPO | |
| SCHEMBL19590602 | 0.82 | TSPO (0.44) | TSPO | |
| SCHEMBL417897 | 0.79 | TSPO (0.71) | TSPO | |
| SCHEMBL11834168 | 0.78 | P2RX4 (0.46) | ALDH1A1 | |
| SCHEMBL413917 | 0.78 | TSPO (0.62) | TSPO | |
| SCHEMBL19590537 | 0.74 | TSPO (0.40) | TSPOALDH1A1 | |
| SCHEMBL412189 | 0.74 | TSPO (0.52) | TSPO | |
| SCHEMBL417887 | 0.72 | TSPO (0.69) | TSPO | |
| SCHEMBL414152 | 0.68 | TSPO (0.69) | TSPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2621544-A1 | IN VIVO IMAGING METHOD FOR CANCER | GE Healthcare UK Limited (GB) | 2013-08-07 | — | — | EP | disclosed |
| WO-2012041953-A1 | IN VIVO IMAGING METHOD FOR CANCER | GE HEALTHCARE LIMITED (GB) | 2012-04-05 | — | — | WO | disclosed |