Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19588482 | 0.90 | HRH3 (0.45) | HRH3MAPTHSD17B10LMNAALDH1A1 | |
| SCHEMBL10928551 | 0.82 | MAPT (0.46) | HRH3MAPTHSD17B10ALDH1A1MEN1 | |
| SCHEMBL17525778 | 0.80 | HRH3 (0.47) | HRH3MAPTHSD17B10ALDH1A1MEN1 | |
| SCHEMBL10159010 | 0.76 | MAPT (0.56) | HRH3MAPTHSD17B10ALDH1A1MEN1 | |
| SCHEMBL2409164 | 0.76 | TSHR (0.47) | HRH3MAPTHSD17B10ALDH1A1TAAR1 | |
| SCHEMBL1383804 | 0.74 | MAPT (0.46) | HRH3MAPTHSD17B10ALDH1A1MEN1 | |
| SCHEMBL14678488 | 0.74 | MGLL (0.52) | HRH3MAPTHSD17B10LMNAALDH1A1 | |
| SCHEMBL266485 | 0.73 | L3MBTL1 (0.64) | MAPTHSD17B10LMNAALDH1A1MEN1 | |
| SCHEMBL13621141 | 0.72 | HRH3 (0.60) | HRH3ALDH1A1DRD3 | |
| SCHEMBL2398501 | 0.71 | GLA (0.52) | MAPTHSD17B10ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9815814-B2 | Glutarimide derivatives, use thereof, pharmaceutical composition based thereon and methods for producing glutarimide derivatives | Obschestvo S Ogranichennoi Otvetstvennostiyu “Pharmenterprises” (RU) | 2017-11-14 | — | — | US | disclosed |