Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | CA12 | O43570 | 2/20 | 0.53 |
| ▸ | CA1 | P00915 | 2/20 | 0.53 |
| ▸ | CA2 | P00918 | 2/20 | 0.53 |
| ▸ | CA7 | P43166 | 2/20 | 0.53 |
| ▸ | CA9 | Q16790 | 2/20 | 0.53 |
| ▸ | EPHX2 | P34913 | 7/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | DHFR | P00374 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10113275 | 0.82 | ALDH1A1 (0.80) | ALDH1A1MAPK1SMN1; SMN2CA12CA1 | |
| SCHEMBL19590946 | 0.80 | HSD17B10 (0.50) | ALDH1A1MAPK1CA12CA1CA2 | |
| SCHEMBL24624914 | 0.74 | ALDH1A1 (0.83) | ALDH1A1MAPK1SMN1; SMN2CA12CA1 | |
| SCHEMBL10112945 | 0.73 | CA1 (0.78) | ALDH1A1MAPK1SMN1; SMN2CA12CA1 | |
| SCHEMBL5348761 | 0.71 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2CA1CA2HTT | |
| SCHEMBL10112998 | 0.70 | CA12 (0.73) | ALDH1A1MAPK1SMN1; SMN2CA12CA1 | |
| SCHEMBL10112982 | 0.70 | ALDH1A1 (0.78) | ALDH1A1MAPK1SMN1; SMN2CA12CA1 | |
| SCHEMBL10113092 | 0.70 | ALDH1A1 (1.00) | ALDH1A1MAPK1SMN1; SMN2CA12CA1 | |
| SCHEMBL10112989 | 0.70 | CA12 (0.71) | ALDH1A1MAPK1SMN1; SMN2CA12CA1 | |
| SCHEMBL23016876 | 0.69 | ALDH1A1 (0.74) | ALDH1A1MAPK1SMN1; SMN2CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9815838-B2 | Methods and compositions for treating pain | HYDRA BIOSCIENCES, INC. (US) | 2017-11-14 | — | — | US | disclosed |